Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

900 questions · 932 findings · 149 reviews

No studies found 215 · 23.1%GRADE not reported 65 · 7%Very low 234 · 25.1%Low 256 · 27.5%Moderate 134 · 14.4%High 28 · 3%

Heated humidification + fixed CPAP vs fixed CPAP

Withdrawals (parallel group trials/first arm cross‐over trials) · adults with a diagnosis of sleep apnoea

It is very uncertain whether heated humidification + fixed CPAP changes withdrawals (parallel group trials/first arm cross‐over trials) compared with fixed CPAP alone (very low certainty).

1 finding from 1 review

Heated humidification + fixed CPAP vs fixed CPAP

Adverse events (machine tolerability outcomes) assessed as number of participants experiencing a blocked nose · adults with a diagnosis of sleep apnoea

Heated humidification + fixed CPAP may leads to lower adverse events (machine tolerability outcomes) assessed as number of… compared with fixed CPAP alone (low certainty).

1 finding from 1 review

Auto‐CPAP vs fixed CPAP

Withdrawals (parallel group trials/first arm cross‐over trials) · adults with a diagnosis of OSA

Auto‐CPAP showed no clear difference in withdrawals (parallel group trials/first arm cross‐over trials) Median compared with fixed CPAP (moderate certainty).

1 finding from 1 review