Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,171 questions · 1,373 findings · 60 reviews · Dental caries

No studies found 282 · 20.5%GRADE not reported 606 · 44.1%Very low 257 · 18.7%Low 160 · 11.7%Moderate 66 · 4.8%High 2 · 0.1%

ART using glass ionomer cement (GIC) vs Amalgam restoration

Pain (permanent, immature teeth) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)

ART using glass ionomer cement (GIC) led to lower pain (permanent, immature teeth) compared with conventional treatment using amalgam; GRADE not reported.

1 finding from 1 review

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Restoration failure (primary dentition) · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

The review found no eligible studies for this question.

1 finding from 1 review

High-viscosity glass-ionomer ART restorations vs Conventional treatment using H-GIC (rotary instruments)

Restoration failure (permanent dentition) · People with dental caries in primary teeth (mainly children)

The review found no eligible studies for this question.

1 finding from 1 review

Metal-free FDPs (zirconia ceramic) vs Metal-ceramic FDPs

Patient satisfaction (measured by patient satisfaction or aesthetic scales) · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)

It is very uncertain whether metal-free FDPs (zirconia ceramic) changes aesthetic evaluation (patient aesthetic satisfaction changes) compared with metal-ceramic FDPs (very low certainty).

1 finding from 1 review

Glass ionomer-based sealant vs Resin-based sealant

Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review

High-viscosity glass-ionomer ART restorations vs Conventional treatment using H-GIC (rotary instruments)

Restoration failure (primary dentition) · People with dental caries in primary teeth (mainly children)

ART using high-viscosity glass ionomer cement (H-GIC), hand… may leads to higher restoration failure (primary dentition) compared with conventional treatment using H-GIC (rotary instruments) (low certainty).

1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs placebo or no treatment

Decayed or filled primary tooth surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)

It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes decayed or filled primary tooth surfaces at 3 years compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Metal-free tooth-supported FDPs (pressed veneering ceramic) vs Metal-free tooth-supported FDPs (layered veneering ceramic)

Bridge complications · Adults (18 years or older) needing a three-unit tooth-supported fixed dental prosthesis

It is very uncertain whether metal-free tooth-supported FDPs (pressed veneering ceramic) changes bridge complications compared with metal-free tooth-supported FDPs (layered veneering ceramic) (very low certainty).

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Participant experience (co-operation during procedure) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)
1 finding from 1 review

Metal-free implant-supported single crowns (zirconia veneered with feldspathic ceramic) vs Metal-ceramic implant-supported single crowns

Implant crown complications · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown

It is very uncertain whether metal-free implant-supported single crowns (zirconia veneered with… changes implant crown complications compared with metal-ceramic implant-supported single crowns (very low certainty).

1 finding from 1 review

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs placebo or no treatment

Decayed or filled primary tooth surfaces at 5 years · Pregnant women (for preventing dental caries in the primary teeth of their children)

It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes decayed or filled primary tooth surfaces at 5 years compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Metal-free single crowns (full-contour zirconia) vs Cast gold (conventional metal) single crowns

Periodontal/peri-implant status and occlusal wear (secondary outcomes) · Adults (18 years or older) needing a single crown in the molar or premolar region

The review found no eligible studies for this question.

1 finding from 1 review