Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,257 questions · 1,337 findings · 183 reviews

No studies found 175 · 13.1%GRADE not reported 212 · 15.9%Very low 286 · 21.4%Low 341 · 25.5%Moderate 254 · 19%High 69 · 5.2%

Decompressive surgery plus radiotherapy vs radiotherapy

Survival (short term) At 30 days · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

Decompressive surgery plus radiotherapy showed no clear difference in survival (short term) At 30 days compared with radiotherapy (low certainty).

1 finding from 1 review

Intervention not reported

Clinical global impression of change ‐ patient's self‐reported impression of memory change · Multiple sclerosis

The intervention showed no clear difference in clinical global impression of change ‐ patient's self‐reported… (high certainty).

1 finding from 1 review

Intervention not reported

Clinical global impression of change ‐ patient's self‐reported impression of cognitive change · Multiple sclerosis

The intervention showed no clear difference in clinical global impression of change ‐ patient's self‐reported… (high certainty).

1 finding from 1 review

Intervention not reported

Clinical global impression of change ‐ clinician's impression of memory change · Multiple sclerosis

The intervention showed no clear difference in clinical global impression of change ‐ clinician's impression of… (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinical global impression of change ‐ clinician's impression of cognitive change · Multiple sclerosis

The intervention leads to higher clinical global impression of change ‐ clinician's impression of… (high certainty).

1 finding from 1 review

Intervention not reported

At least 50% reduction in pain · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review

Intervention not reported

At least 30% reduction in pain · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review

Intervention not reported

Proportion below 30/100 mm on VAS · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Patient Global Impression of Change very much improved (patient global evaluation of pain relief complete or good) · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review

Intervention not reported

Patient Global Impression of Change much or very much improved (patient global evaluation of pain relief complete, good or moderate) · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review

Intervention not reported

Any measure of 'substantial' pain relief · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review

Intervention not reported

Adverse event withdrawals · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…

It is very uncertain whether the intervention changes adverse event withdrawals (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review