Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Ocrelizumab vs placebo

Number of participants with new or enlarging T2‐hyperintense lesions on MRI · primary progressive multiple sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Ocrelizumab vs interferon beta‐1a

Number of participants with new or enlarging T2‐hyperintense lesions on MRI · patients with relapsing‐remitting multiple sclerosis

Ocrelizumab may leads to lower number of participants with new or enlarging T2‐hyperintense lesions… compared with interferon beta‐1a (low certainty).

1 finding from 1 review

Mindfulness vs control

Smoking cessation · people who smoke

Mindfulness training showed no clear difference in mindfulness training vs matched‐intensity smoking cessation… compared with control (low certainty).

2 findings from 1 review

Distress tolerance training vs control

Smoking cessation · people who smoke

Distress tolerance training showed no clear difference in distress tolerance training vs matched‐intensity smoking cessation… compared with control (low certainty).

2 findings from 1 review

Yoga vs control

Smoking cessation · people who smoke

It is very uncertain whether yoga changes yoga vs matched‐intensity smoking cessation treatment: smoking… compared with control (very low certainty).

1 finding from 1 review