Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,793 questions · 1,866 findings · 339 reviews

No studies found 245 · 13.1%GRADE not reported 142 · 7.6%Very low 612 · 32.8%Low 513 · 27.5%Moderate 305 · 16.3%High 49 · 2.6%

RISPERIDONE DEPOT vs RISPERIDONE

Adverse events: Movement disorder ‐ any extra pyramidal symptoms ‐ short term · patients with schizophrenia

RISPERIDONE DEPOT showed no clear difference in adverse events: Movement disorder ‐ any extra pyramidal symptoms ‐… compared with ORAL RISPERIDONE (moderate certainty).

1 finding from 1 review

RISPERIDONE DEPOT vs placebo

Leaving the study early · patients with schizophrenia

It is very uncertain whether RISPERIDONE DEPOT changes leaving the study early: Any reason ‐ all doses risperidone depot ‐… compared with PLACEBO (very low certainty).

1 finding from 1 review

RISPERIDONE DEPOT vs placebo

Adverse events: General: Severe adverse event ‐ any dose risperidone depot ‐ short term Spontaneous reporting by study participants · patients with schizophrenia

It is very uncertain whether RISPERIDONE DEPOT changes adverse events: General: Severe adverse event ‐ any dose risperidone… compared with PLACEBO (very low certainty).

1 finding from 1 review

RISPERIDONE DEPOT vs placebo

Adverse events: Specific: Weight gain ‐ all doses of depot risperidone ‐ short term Spontaneous reporting by study participants · patients with schizophrenia

It is very uncertain whether RISPERIDONE DEPOT changes adverse events: Specific: Weight gain ‐ all doses of depot… compared with PLACEBO (very low certainty).

1 finding from 1 review

Intervention not reported

Pain intensity (VAS) short term · patients with chronic mechanical neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Disability (neck and pain disability scale) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Quality of life (SF‐36 mental score) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Disability (NPQ) short term · patients with chronic mechanical neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Disability (NDI) short term · patients with chronic mechanical neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Quality of life (SF‐36) short term · patients with chronic mechanical neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Pain intensity (VAS) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Pain pressure threshold short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Disability (NDI) short term Function (NPQ) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Quality of life (SF‐36, Functional Component) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Pain intensity (VAS) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Cannabis use frequency at short‐term · adults with cannabis use disorder or frequent cannabis use

The intervention probably leads to higher cannabis use frequency at short‐term (moderate certainty).

1 finding from 1 review