Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

84 questions · 86 findings · 6 reviews

No studies found 14 · 16.3%GRADE not reported 1 · 1.2%Very low 3 · 3.5%Low 23 · 26.7%Moderate 30 · 34.9%High 15 · 17.4%

Summary of findings ‐ triple therapy: elexacaftor‐tezacaftor‐ivacaftor/deutivacaftor vs control

Time to first pulmonary exacerbation · adults with cystic fibrosis and either F508del/MF or F508del/F508del genotype

The review found no eligible studies for this question.

1 finding from 1 review

Platinum‐containing chemotherapy vs chemotherapy without platinum

Disease-free survival · neoadjuvant therapy for early triple‐negative breast cancer

Platinum‐containing chemotherapy leads to lower DFS at 2 years compared with chemotherapy without platinum (high certainty).

2 findings from 1 review

Platinum‐containing chemotherapy vs chemotherapy without platinum

Disease-free survival · early triple‐negative breast cancer

Platinum‐containing chemotherapy leads to lower DFS at 2 years compared with chemotherapy without platinum (high certainty).

2 findings from 1 review