Cochrane · systematic review · CD009034
Sequential versus standard triple first‐line therapy for Helicobacter pylori eradication
Nyssen, OP, McNicholl, AG, Megraud, F, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 16.7%Low 1 · 16.7%Moderate 2 · 33.3%High 2 · 33.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Is 10‐day SEQ efficacy superior to STT?
Population: participants with Helicobacter pylori infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Eradication proportion | RD 0.09 | 44 studies · 12701 participants | Moderate Downgraded: inconsistency |
Geographic region | RD 0.09 | 44 studies · 12284 participants | Low Downgraded: imprecision |
Publication date | RD 0.08 | 44 studies · 12751 participants | Moderate Downgraded: imprecision, inconsistency |
STT length | RD 0.14 | 22 studies · 5439 participants | High |
Bacterial antibiotic resistance | RD 0.13 | 8 studies · 832 participants | Very low Downgraded: imprecision, inconsistency |
Adverse events rate | RD 0 | 27 studies · 8103 participants | High |