Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

177 questions · 178 findings · 33 reviews · Headline outcomes only

No studies found 62 · 34.8%GRADE not reported 10 · 5.6%Very low 47 · 26.4%Low 40 · 22.5%Moderate 18 · 10.1%High 1 · 0.6%

Low‐intensity pulsed ultrasound vs control

Delayed or non‐union (medium term) · acute fractures in adults; included studies assessed effects in complete upper limb fractures (distal radius, clavicle, scaphoid,…

Low‐intensity pulsed ultrasound showed no clear difference in delayed or non‐union (medium term) compared with control (moderate certainty).

1 finding from 1 review

Low‐intensity pulsed ultrasound vs control

Adverse events ‐ total of adverse events (Skin irritation) · acute fractures in adults; included studies assessed effects in complete upper limb fractures (distal radius, clavicle, scaphoid,…

It is very uncertain whether low‐intensity pulsed ultrasound changes adverse events Reported as skin irritation compared with control (very low certainty).

1 finding from 1 review

Monthly pulsed high‐dose dexamethasone vs prednisolone

≥ 1 point improvement on INCAT disability score at 12 months · patients with chronic inflammatory demyelinating polyradiculoneuropathy

Monthly pulsed high‐dose dexamethasone may leads to higher ≥ 1 point improvement on INCAT disability score at 12 months compared with oral prednisolone (low certainty).

1 finding from 1 review

Pulsed electromagnetic field therapy (PEMF) vs placebo

Function Total recovery of joint function · patients with adhesive capsulitis (frozen shoulder)

It is very uncertain whether pulsed electromagnetic field therapy (PEMF) changes function Total recovery of joint function compared with placebo (very low certainty).

1 finding from 1 review

Pulsed electromagnetic field therapy (PEMF) vs placebo

Participant‐reported pain relief ≥ 30% Complete resolution of SPADI pain · patients with adhesive capsulitis (frozen shoulder)

It is very uncertain whether pulsed electromagnetic field therapy (PEMF) changes participant‐reported pain relief ≥ 30% Complete resolution of SPADI… compared with placebo (very low certainty).

1 finding from 1 review