Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

256 questions · 278 findings · 34 reviews · ENT

No studies found 86 · 30.9%GRADE not reported 1 · 0.4%Very low 88 · 31.7%Low 66 · 23.7%Moderate 35 · 12.6%High 2 · 0.7%

Intratympanic corticosteroids vs no treatment or versus placebo

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs no treatment or versus placebo

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Proportion of susceptible participants who did not experience any motion sickness symptoms under natural conditions Assessed by: self‐reported questionnaires6,7 · patients with motion sickness

Antihistamines probably leads to higher proportion of susceptible participants who did not experience any… compared with placebo (moderate certainty).

1 finding from 1 review

Antihistamines vs placebo

Proportion of susceptible participants who did not experience any motion sickness symptoms under experimental conditions Assessed by: calculated based on head movements tolerated (rotating chair); MSAQ · patients with motion sickness
1 finding from 1 review

Antihistamines vs placebo

Proportion of susceptible participants who experienced a reduction or resolution of existing motion sickness symptoms · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review