Question · asked by 1 review

Antihistamines vs placebo: Proportion of susceptible participants who did not experience any motion sickness symptoms under natural conditions Assessed by: self‐reported questionnaires6,7

Population
patients with motion sickness
Intervention
Antihistamines
Comparison
placebo
Outcome
Proportion of susceptible participants who did not experience any motion sickness symptoms under natural conditions Assessed by: self‐reported questionnaires6,7

Antihistamines probably leads to higher proportion of susceptible participants who did not experience any… compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Antihistamines vs placebo
Proportion of susceptible participants who did not experience any motion sickness symptoms under natural conditions Assessed by: self‐reported questionnaires6,7 · patients with motion sickness
Antihistamines probably leads to higher proportion of susceptible participants who did not experience any… compared with placebo (moderate certainty).
Antihistamines for motion sickness (2022) · Cochrane Headline outcomes only
RR 1.81 [1.23, 2.66]3 studies · 240 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antihistamines for motion sickness
2022 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.