Secondary outcome: acceptability of treatment · ulceration and other skin changes caused by nerve damage in leprosy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cost of the intervention · ulceration and other skin changes caused by nerve damage in leprosy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain, number of ulcers, ulcer-free days and ulcer size · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
A single trial at high risk of bias compared pentoxifylline 400 mg three times daily (n=14) with placebo (n=12). No statistically significant differences were reported for pain, number of ulcers and ulcer-free days at…
1 study · 26 participants
GRADE not reported
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Patients receiving pentoxifylline reported more adverse events than those in the placebo group but this was not statistically significant (69% reported adverse effects: dizziness, headaches, stomach upset, increased…
1 study · 26 participants
GRADE not reported
Complete cure, at least 3 months after the end of treatment · People with American cutaneous leishmaniasis
Pentoxifylline (oral 400 mg thrice daily) plus meglumine antimoniate… showed no clear difference in complete cure, at least 3 months after the end of treatment compared with IMMA plus placebo (moderate certainty).
1 finding from 1 review
Adverse effects · People with American cutaneous leishmaniasis
1 finding from 1 review
Recurrence ‐ not measured · People with American cutaneous leishmaniasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Albumin plus midodrine plus octreotide plus pentoxifylline (No RCTs) · people with hepatorenal syndrome with decompensated liver cirrhosis
It is very uncertain whether the intervention changes albumin plus midodrine plus octreotide plus pentoxifylline (No RCTs) (very low certainty).
1 finding from 1 review
HR 0.5 [0.06, 4.07]
Studies not reported
Very low
Absolute claudication distance (change in metres) · intermittent claudication
1 finding from 1 review
Arterial revascularisation · intermittent claudication
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Amputation · intermittent claudication
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse event related to study medication ‐ headache (number of cases) · intermittent claudication
Cilostazol may leads to higher adverse event related to study medication ‐ headache (number of cases) compared with pentoxifylline (low certainty).
1 finding from 1 review
Cardiovascular events · intermittent claudication
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in claudication distance from baseline (m) · intermittent claudication
1 finding from 1 review
Quality of life (change in points, SF‐36, WIQ) · intermittent claudication
1 finding from 1 review
Adverse events (participants) · people with critical limb ischaemia
It is very uncertain whether prostanoids changes adverse events (participants) compared with pentoxifylline (very low certainty).
1 finding from 1 review
Rest‐pain relief · people with critical limb ischaemia
It is very uncertain whether prostanoids changes rest‐pain relief compared with pentoxifylline (very low certainty).
1 finding from 1 review
Ulcer healing · people with critical limb ischaemia
It is very uncertain whether prostanoids changes ulcer healing compared with pentoxifylline (very low certainty).
1 finding from 1 review
Cardiovascular mortality · people with critical limb ischaemia
The review found no eligible studies for this question.
1 finding from 1 review
Amputation · people with critical limb ischaemia
It is very uncertain whether prostanoids changes total amputations compared with pentoxifylline (very low certainty).
1 finding from 1 review