Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

74 questions · 76 findings · 15 reviews · Vascular

No studies found 15 · 19.7%GRADE not reported 7 · 9.2%Very low 13 · 17.1%Low 19 · 25%Moderate 22 · 28.9%High 0 · 0%

Ultrasound‐assisted catheter‐directed thrombolysis plus standard intravenous heparinisation vs standard intravenous heparinisation

Recurrent APE requiring retreatment or change to a different APE treatment ( · people with intermediate‐risk (submassive) APE
1 finding from 1 review

Retrievable vena caval filters with anticoagulation vs anticoagulation

Mortality (up to 6 months) · participants with unprovoked acute symptomatic PE and at high risk for recurrent PEa

Retrievable vena caval filters with anticoagulation showed no clear difference in mortality (up to 6 months) compared with anticoagulation (moderate certainty).

1 finding from 1 review

Retrievable vena caval filters with anticoagulation vs anticoagulation

Symtomatic lower extremity venous thrombosis confirmed by Doppler ultrasound or venography (up to 6 months) · participants with unprovoked acute symptomatic PE and at high risk for recurrent PEa

Retrievable vena caval filters with anticoagulation showed no clear difference in symtomatic lower extremity venous thrombosis confirmed by Doppler… compared with anticoagulation (moderate certainty).

1 finding from 1 review

Retrievable vena caval filters with anticoagulation vs anticoagulation

Major bleeding · participants with unprovoked acute symptomatic PE and at high risk for recurrent PEa

Retrievable vena caval filters with anticoagulation showed no clear difference in major bleedingc (up to 6 months) compared with anticoagulation (moderate certainty).

1 finding from 1 review