Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

109 questions · 115 findings · 13 reviews

No studies found 9 · 7.8%GRADE not reported 4 · 3.5%Very low 28 · 24.3%Low 40 · 34.8%Moderate 22 · 19.1%High 12 · 10.4%

Oral omega‐3 PUFAs plus conventional therapy vs conventional therapy

Dry eye symptoms, measured using the OSDI score (ranging from 0 to 100 units, with a reduction in scores indicating clinical improvement) at 1‐month (with actual · people with dry eyea

Oral omega‐3 PUFAs plus conventional therapy showed no clear difference in dry eye symptoms, measured using the OSDI score (ranging from 0 to… compared with conventional therapy alone (low certainty).

1 finding from 1 review

Oral long‐chain omega‐3 PUFAs vs placebo or no treatment

Change in dry eye symptoms, measured using the OSDI score (ranging from 0 to 100 units, with a reduction in score indicating clinical improvement) at 1‐month (with actual · people with dry eyea

Oral long‐chain omega‐3 PUFAs (ie, EPA and DHA) showed no clear difference in change in dry eye symptoms, measured using the OSDI score (ranging… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Oral long‐chain omega‐3 PUFAs vs placebo or no treatment

Change in ocular surface staining at 1‐month (with actual · people with dry eyea

Oral long‐chain omega‐3 PUFAs (ie, EPA and DHA) showed no clear difference in change in ocular surface staining at 1‐month (with actual compared with placebo or no treatment (low certainty).

1 finding from 1 review

Oral long‐chain omega‐3 PUFAs vs placebo or no treatment

Change in tear osmolarity (measured in mOsmol/L, with reductions in osmolarity indicating clinical improvement) at 1‐month (with actual · people with dry eyea

Oral long‐chain omega‐3 PUFAs (ie, EPA and DHA) showed no clear difference in change in tear osmolarity (measured in mOsmol/L, with reductions in… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Dental caries vs Caries-free controls

Oral health-related quality of life · Indians

In adolescents (10-19 years), dental caries was associated with poorer OHRQoL (pooled OR 3.92; 5 studies); ungraded.

5 findings from 1 review
Show 2 more findings

Dental caries vs Caries-free controls

Oral health-related quality of life · Indian children aged 3-5 years

In children aged 3-5 years, early childhood caries was significantly associated with poorer OHRQoL (narrative; 3 studies); ungraded.

1 finding from 1 review