Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

114 questions · 114 findings · 9 reviews · Eyes and Vision

No studies found 51 · 44.7%GRADE not reported 5 · 4.4%Very low 18 · 15.8%Low 21 · 18.4%Moderate 18 · 15.8%High 1 · 0.9%

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery probably leads to higher proportion of participants who were medication‐free (not using… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in unmedicated IOP24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in unmedicated IOP24 months (medium‐term) compared with phacoemulsification alone (high certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in daily IOP‐lowering medicationsat 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in daily IOP‐lowering medicationsat 24 months… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who required further glaucoma surgery, including laser · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants who required further glaucoma surgeryat… compared with phacoemulsification alone (low certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants experiencing postoperative complicationsover 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants experiencing postoperative… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Cataract surgery with Hydrus microstent probably leads to higher proportion of participants who were medication‐free (not using eye… compared with cataract surgery alone (moderate certainty).

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Glaucoma progression at 12 months, measured by additional visual field defects · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Mean change in health‐related quality of life · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Proportion of participants who required further glaucoma surgery, including laser · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Cataract surgery with Hydrus microstent may leads to lower proportion of participants who required further glaucoma surgery,… compared with cataract surgery alone (low certainty).

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Glaucoma progression at 12 months, measured by additional visual field defects · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review