What do systematic reviews say?

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement

The review found no eligible studies for this question.

• Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement

• Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 278 participants
  Very low

Multiple micronutrients vs placebo

Multiple micronutrients showed no clear difference in mortality compared with placebo (low certainty).

• Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
  RR 0.91 [0.72, 1.15]
  7 studies · 2897 participants
  Low

Multiple micronutrients vs placebo

It is very uncertain whether multiple micronutrients changes hospital admissions compared with placebo (very low certainty).

• Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
  RR 0.86 [0.61, 1.22]
  2 studies · 881 participants
  Very low

Multiple micronutrients vs placebo

• Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 1581 participants
  Low

Multiple micronutrients vs placebo

• Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 840 participants
  Moderate

Multiple micronutrients vs placebo

• Micronutrient supplementation in adults with HIV infection 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1007 participants
  Very low

Are disease‐modifying drugs for a first attack suggestive of multiple sclerosis (MS) effective and safe vs placebo?

It is very uncertain whether are disease‐modifying drugs for a first attack suggestive of… changes disability‐worsening Proportion of participants with… compared with placebo? (very low certainty).

• Treatment with disease‐modifying drugs for people with a first clinical attack suggestive of multiple sclerosis 2017 · Cochrane Headline outcomes only
  OR 0.74 [0.49, 1.14]
  Studies not reported
  Very low

Are disease‐modifying drugs for a first attack suggestive of multiple sclerosis (MS) effective and safe vs placebo?

It is very uncertain whether are disease‐modifying drugs for a first attack suggestive of… changes relapse Proportion of participants with relapse during 24 months of… compared with placebo? (very low certainty).

• Treatment with disease‐modifying drugs for people with a first clinical attack suggestive of multiple sclerosis 2017 · Cochrane Headline outcomes only
  OR 0.65 [0.38, 1.12]
  Studies not reported
  Very low

Are disease‐modifying drugs for a first attack suggestive of multiple sclerosis (MS) effective and safe vs placebo?

Are disease‐modifying drugs for a first attack suggestive of… showed no clear difference in occurrence of at least one serious adverse event Proportion of… compared with placebo? (low certainty).

• Treatment with disease‐modifying drugs for people with a first clinical attack suggestive of multiple sclerosis 2017 · Cochrane Headline outcomes only
  OR 0.78 [0.6, 1.03]
  Studies not reported
  Low

Are disease‐modifying drugs for a first attack suggestive of multiple sclerosis (MS) effective and safe vs placebo?

It is very uncertain whether are disease‐modifying drugs for a first attack suggestive of… changes withdrawls or drug discontinuation due to adverse events during 24… compared with placebo? (very low certainty).

• Treatment with disease‐modifying drugs for people with a first clinical attack suggestive of multiple sclerosis 2017 · Cochrane Headline outcomes only
  OR 2.43 [0.91, 6.49]
  Studies not reported
  Very low

(ITS) Multiple safe devices vs regular devices

• Devices for preventing percutaneous exposure injuries caused by needles in healthcare personnel 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2 participants
  Very low

(ITS) Multiple safe devices vs regular devices

• Devices for preventing percutaneous exposure injuries caused by needles in healthcare personnel 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 2 participants
  Very low

(ITS) Multiple safe devices vs regular devices

It is very uncertain whether (CBA) Multiple safe devices changes needle stick injuries compared with regular devices (very low certainty).

• Devices for preventing percutaneous exposure injuries caused by needles in healthcare personnel 2017 · Cochrane Headline outcomes only
  Rate ratio 0.11 [0.01, 0.81]
  1 study · 1 participants
  Very low

Multiple doses of deworming drugs vs placebo

• Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas 2019 · Cochrane Headline outcomes only
  no estimate extracted
  18 studies · 52448 participants
  Very low

Multiple doses of deworming drugs vs placebo

• Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas 2019 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 13700 participants
  Moderate

Multiple doses of deworming drugs vs placebo

• Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas 2019 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 5498 participants
  Moderate

Multiple doses of deworming drugs vs placebo

• Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas 2019 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 35394 participants
  Moderate

Multiple doses of deworming drugs vs placebo

• Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Multiple doses of deworming drugs vs placebo

• Public health deworming programmes for soil‐transmitted helminths in children living in endemic areas 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 20650 participants
  Very low