Self‐reported pain (dysmenorrhoea) (dichotomous data) ‐ reduction of pain to zero at 6 months' · women with endometriosis
It is very uncertain whether combined oral contraceptive pill changes self‐reported pain (dysmenorrhoea) (dichotomous data): reduction of… compared with other medical treatment (very low certainty).
2 findings from 1 review
Menstrual regularity at 12 months Laser LOD vs harmonic scalpel N of participants: 34 (1 RCT) · Women with symptoms of PCOS
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Improvement in androgenic symptoms · Women with symptoms of PCOS
LOD showed no clear difference in improvement in androgenic symptoms at 6 months (hirsutism/acne) ‐… compared with medical interventions (low certainty).
2 findings from 1 review
OR 1 [0.42, 2.37]
Studies not reported
Low
OR 3.2 [0.33, 30.94]
Studies not reported
Very low
Harms: GI Upset at 6 months ‐ LOD vs metformin + clomiphene N of participants: 332 (2 RCTs) Harms: OHSS rates at 6 months ‐ LOD vs gonadotrophins N of participants: 33 (1 RCT) · Women with symptoms of PCOS
LOD probably leads to lower harms: GI Upset at 6 months ‐ LOD vs metformin + clomiphene N of… compared with medical interventions (moderate certainty).
1 finding from 1 review
OR 0.05 [0.01, 0.36]
Studies not reported
Moderate
Uterine fibroid‐related symptoms (abnormal uterine bleeding, measured at 12 weeks, with the pictorial blood assessment chart (PBAC); lower = better) · women with uterine fibroids
2 findings from 1 review
Adverse events (spotting at 3 and 6 months) · women with uterine fibroids
1 finding from 1 review
Uterine fibroid‐related symptoms (duration of uterine bleeding, measured at 12 weeks; lower = better) · women with uterine fibroids
1 finding from 1 review
Uterine fibroid‐related symptoms (abnormal uterine bleeding, measured at 12 weeks, with the pictorial blood assessment chart (PBAC); lower = better) · women with uterine fibroids
1 finding from 1 review
Fibroid size · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events (hot flushes) · women with uterine fibroids
1 finding from 1 review
Haemoglobin level ‐ Haemoglobin level at 12 months Scale from: 0 to 20. · women with uterine fibroids
1 finding from 1 review
Fibroid size · women with uterine fibroids
1 finding from 1 review
Adverse events · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in fibroid related symptoms · women with uterine fibroids
1 finding from 1 review
Change in haemoglobin level from baseline · women with uterine fibroids
2 findings from 1 review
Fibroid size · women with uterine fibroids
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Uterine volume (cm³) · women with uterine fibroids
1 finding from 1 review
Operating time · women with uterine fibroids
3 findings from 1 review
no estimate extracted
6 studies · 443 participants
Very low
no estimate extracted
1 study · 39 participants
Low
no estimate extracted
6 studies · 617 participants
Low
Intraoperative blood loss (mL) · women with uterine fibroids
3 findings from 1 review
Blood transfusion · women with uterine fibroids
GnRHa treatment showed no clear difference in blood transfusions compared with no pretreatment or placebo before myomectomy (operative and… (low certainty).
3 findings from 1 review