Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

99 questions · 105 findings · 7 reviews · Fertility Regulation

No studies found 38 · 36.2%GRADE not reported 0 · 0%Very low 15 · 14.3%Low 36 · 34.3%Moderate 14 · 13.3%High 2 · 1.9%

Mifepristone (600 mg) plus prostaglandin vs mifepristone (200 mg) plus prostaglandin

Failure to achieve complete abortion · women undergoing first trimester abortion

Mifepristone (600 mg) plus prostaglandin showed no clear difference in failure to achieve complete abortion compared with mifepristone (200 mg) plus prostaglandin (moderate certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Failure to achieve complete abortion · women undergoing first trimester abortion

Oral misoprostol probably leads to higher failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty).

2 findings from 1 review

Sublingual misoprostol vs vaginal misoprostol

Women's dissatisfaction with the procedure · women undergoing first trimester abortion

Sublingual misoprostol showed no clear difference in women's dissatisfaction with the procedure compared with vaginal misoprostol (moderate certainty).

1 finding from 1 review