Clinician's assessment of improvement of hirsutism Ferriman‐Gallwey score Scale from: 0 to 36 · women with hirsutism
1 finding from 1 review
Change in serum androgen levels · women with hirsutism
1 finding from 1 review
Change in BMI · women with hirsutism
1 finding from 1 review
Improvement of other clinical signs of hyperandrogenism ‐ not measured · women with hirsutism
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Primary outcome: Global improvement of disease activity or damage assessed by a medical practitioner or by participants · children and adolescents with active morphea (linear scleroderma, generalised morphea and mixed subtype: linear and circumscribed).
Oral methotrexate and oral prednisone may leads to higher primary outcome: Global improvement of disease activity or damage… compared with placebo and oral prednisone (low certainty).
1 finding from 1 review
Adverse events associated with treatment · children and adolescents with active morphea (linear scleroderma, generalised morphea and mixed subtype: linear and circumscribed).
Oral methotrexate and oral prednisone showed no clear difference in primary outcome: Adverse effects compared with placebo and oral prednisone (low certainty).
1 finding from 1 review
Secondary outcome: Improvement of disease activity (reduction in lesion size) · children and adolescents with active morphea (linear scleroderma, generalised morphea and mixed subtype: linear and circumscribed).
1 finding from 1 review
Secondary outcome: Improvement of disease damage ‐ not measured · children and adolescents with active morphea (linear scleroderma, generalised morphea and mixed subtype: linear and circumscribed).
1 finding from 1 review
Side effects · People with erosive oral lichen planus
1 finding from 1 review
Table 3 (Side-effects). Malhotra 2008: betamethasone oral mini-pulse - transient oedema over the face (7), oedema over hands and feet (4), epigastric discomfort (7), weakness/fatigue (5), loose stools (1), headache…
1 study · 22 participants
GRADE not reported
Investigator‐ or physician‐rated global assessment of disease severity · People with erosive oral lichen planus
Betamethasone oral mini-pulse therapy led to higher physician Global Assessment (clinical severity, 0-12 score) compared with topical triamcinolone acetonide 0.1% paste; GRADE not reported.
1 finding from 1 review
Cosmetic outcome (good/excellent) · adults with basal cell carcinoma of the skin
Radiotherapy probably leads to lower cosmetic outcome (good/excellent) compared with surgical excision (with or without frozen section margin control) (moderate certainty).
1 finding from 1 review
Cosmesis · adults with basal cell carcinoma of the skin
MAL‐PDT probably leads to higher cosmetic outcome (excellent/good) compared with surgical excision (moderate certainty).
1 finding from 1 review
Cosmesis · adults with basal cell carcinoma of the skin
Imiquimod cream showed no clear difference in cosmetic outcome (excellent/good) compared with MAL‐PDT (moderate certainty).
1 finding from 1 review
Cosmesis · adults with basal cell carcinoma of the skin
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Low
Cosmetic outcome (good/excellent) · adults with basal cell carcinoma of the skin
Imiquimod may leads to higher cosmetic outcome (good/excellent) compared with surgical excision (low certainty).
1 finding from 1 review
Intervention not reported
Transepidermal water loss (TEWL) Measured using temperature‐adjusted g/m²/h with the Tewameter TM 300 (Courage + Khazaka, Cologne, Germany) Hahnel 2017: measured at 56 ± 4 days Shishido 2017: measured 15 minutes after wiping the skin with a dry to... · people 60 years of age and older
1 finding from 1 review
Intervention not reported
Stratum corneum hydration (SCH) (at baseline and day 56 ± 4) Hahnel 2017: measured at 56 ± 4 days in mid‐volar arm and lower leg in arbitrary units from 0 (no water) to 120 (on water) using the Corneometer CM 825 Gillis 2016: measured at 12 weeks ... · people 60 years of age and older
1 finding from 1 review
Cosmetic appearance of the hair or participant satisfaction · women with FPHL
1 finding from 1 review
Cosmetic appearance of the hair or participant satisfaction · women with FPHL
Finasteride showed no clear difference in cosmetic appearance of the hair or participant satisfaction compared with placebo (low certainty).
1 finding from 1 review
Cosmetic appearance of the hair or participant satisfaction · women with FPHL
1 finding from 1 review