Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

87 questions · 95 findings · 18 reviews · Anaesthesia

No studies found 5 · 5.3%GRADE not reported 2 · 2.1%Very low 28 · 29.5%Low 39 · 41.1%Moderate 21 · 22.1%High 0 · 0%

Propofol vs sevoflurane

Adverse event ‐ haemodynamic changes, number of events · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol may leads to higher adverse event ‐ haemodynamic changes, number of events compared with sevoflurane (low certainty).

1 finding from 1 review

Propofol vs sevoflurane

Adverse event ‐ pain, visual analogue scale · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol showed no clear difference in adverse event ‐ pain, visual analogue scale compared with sevoflurane (low certainty).

1 finding from 1 review

Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O

Number of patients with postoperative nausea and vomiting (postoperative care unit) · paediatric

Induction and maintenance: sevoflurane + nitrous oxide (N2O) may leads to higher postoperative nausea and vomiting compared with propofol + N2O (low certainty).

1 finding from 1 review

Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O

Postoperative behavioural disturbances Different scales · paediatric

It is very uncertain whether induction and maintenance: sevoflurane + nitrous oxide (N2O) changes postoperative behavioural disturbances Different scales compared with propofol + N2O (very low certainty).

1 finding from 1 review

Induction and maintenance: sevoflurane + nitrous oxide (N2O) vs propofol + N2O

Intraoperative and postoperative respiratory and cardiovascular complications · paediatric

It is very uncertain whether induction and maintenance: sevoflurane + nitrous oxide (N2O) changes intraoperative and postoperative respiratory and cardiovascular… compared with propofol + N2O (very low certainty).

1 finding from 1 review