Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,736 questions · 15,265 findings · 1,163 reviews · Headline outcomes only

No studies found 3,871 · 25.4%GRADE not reported 810 · 5.3%Very low 4,242 · 27.8%Low 3,879 · 25.4%Moderate 1,999 · 13.1%High 464 · 3%

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Intervention vs usual care

Exacerbations (number of people experiencing ≥ 1 exacerbations) · COPD and at least one other long‐term condition

It is very uncertain whether intervention changes exacerbations ‐ number of people experiencing one or more  compared with usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Recovery from CMD ‐ intermediate term (1 to 6 months post intervention) Recovery defined by GDS ≤ 11a; HDRS < 7b; HDRS < 8c; PHQ‐9 < 6d; PHQ‐9 < 5 or 50% reduction from baselinee (RR > 1 denotes greater likelihood of recovery) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to higher recovery from CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Prevalence of CMDs ‐ intermediate term (1 to 6 months post intervention) Diagnosis defined by SRQ‐20 > 7b; PHQ‐9 ≥ 11d (RR < 1 denotes lower prevalence compared to control) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to lower prevalence of CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Severity of CMD symptoms (including anxiety and depression) ‐ intermediate term (1 to 6 months post intervention) Measured by PHQ‐9a,d,f; SRQ‐20b (higher score, higher severity) · adults with common mental disorders
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

PTS symptoms ‐ intermediate term (1 to 6 months post intervention) PCL‐5a,d,e; PCL‐6f; Post‐traumatic Stress Diagnostic Scaleb (higher score = higher severity) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with post‐traumatic stress and CMDs
1 finding from 1 review