Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

105 questions · 107 findings · 11 reviews · Schizophrenia

No studies found 35 · 32.7%GRADE not reported 13 · 12.1%Very low 27 · 25.2%Low 26 · 24.3%Moderate 6 · 5.6%High 0 · 0%

Technology‐mediated psychoeducation + standard care intervention vs usual care

Compliance/satisfaction: medication ‐ not compliant ‐ long‐term · schizophrenia

It is very uncertain whether technology‐mediated psychoeducation + standard care intervention changes compliance/satisfaction: medication ‐ not compliant ‐ long‐term compared with standard care intervention (very low certainty).

1 finding from 1 review

Technology‐mediated psychoeducation + standard care intervention vs usual care

Clinical response: no clinically significant response in mental state · schizophrenia

Technology‐mediated psychoeducation + standard care intervention showed no clear difference in mental state: not improved ‐ short‐term BPRS compared with standard care intervention (low certainty).

1 finding from 1 review

Active education + Support for implementation vs Routine care or Passive dissemination

Process outcome, Practitioner Impact 1. Polypharmacy at · patients with schizophrenia or related psychoses

It is very uncertain whether active education + Support for implementation changes process outcome, Practitioner Impact 1. Polypharmacy at compared with routine care or Passive dissemination (very low certainty).

1 finding from 1 review

Active education + Support for implementation vs Routine care or Passive dissemination

Process outcome, Practitioner Impact: 2. Not screened for cardiovascular risk, Framingham score (corrected for design effect) · patients with schizophrenia or related psychoses

It is very uncertain whether active education + Support for implementation changes process outcome, Practitioner Impact: 2. Not screened for… compared with routine care or Passive dissemination (very low certainty).

1 finding from 1 review

Active education + Support for implementation vs Routine care or Passive dissemination

Patient outcome: treatment adherence: not adherent at · patients with schizophrenia or related psychoses

It is very uncertain whether active education + Support for implementation changes patient outcome: treatment adherence: not adherent at compared with routine care or Passive dissemination (very low certainty).

1 finding from 1 review

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)

Service use: Number of participants needing admission · Adolescents with psychosis

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) showed no clear difference in service use: Number of participants needing admission compared with NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term) (low certainty).

1 finding from 1 review

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)

Leaving the study early · Adolescents with psychosis

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) showed no clear difference in leaving the study early: For any reason compared with NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term) (low certainty).

1 finding from 1 review