Findings

What do systematic reviews say?

1,181 questions · 1,197 findings · 144 reviews

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No studies found 196 · 16.4%GRADE not reported 213 · 17.8%Very low 274 · 22.9%Low 296 · 24.7%Moderate 171 · 14.3%High 47 · 3.9%

Intervention not reported

Total studies: 18 RCTs Total participants: 4440 Number of treatments: 13 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 4440 participants
GRADE not reported

Intervention not reported

Total studies: 28 RCTs Total participants: 10,766 Number of treatments: 22 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
28 studies · 10766 participants
GRADE not reported

Intervention not reported

Total studies: 61 RCTs Total participants: 19,423 Number of treatments: 27 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
61 studies · 19423 participants
GRADE not reported

Intervention not reported

Total studies: 208 RCTs Total participants: 42,445 Number of treatments: 53 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
208 studies · 42445 participants
GRADE not reported

Intervention not reported

Severe skin drug‐induced rash · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The review found no eligible studies for this question.

1 finding from 1 review

Genetic testing for prevention of severe drug‐induced skin rash 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Hospitalisation for drug‐induced skin reaction · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The review found no eligible studies for this question.

1 finding from 1 review

Genetic testing for prevention of severe drug‐induced skin rash 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Motivational interviewing/mindfulness and cognitive skills vs treatment

Positive drug screen or refusal to provide a urine sample · drug‐using offenders with co‐occurring mental health problems

1 finding from 1 review

Interventions for drug‐using offenders with co‐occurring mental health problems 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 84 participants
Very low

Multi‐systemic therapy involving family and juveniles vs treatment

Drug dependence · drug‐using offenders with co‐occurring mental health problems

1 finding from 1 review

Interventions for drug‐using offenders with co‐occurring mental health problems 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 156 participants
Low

Community‐based buprenorphine vs placebo

Drug use · female offenders

It is very uncertain whether community‐based buprenorphine changes end of treatment drug use compared with placebo (very low certainty).

1 finding from 1 review

Interventions for female drug‐using offenders 2019 · Cochrane Headline outcomes only
RR 0.57 [0.27, 1.2]
1 study · 36 participants
Very low

Motivational interviewing vs treatment

Retention [ · concurrent problem alcohol and illicit drug users

Motivational interviewing (MI) showed no clear difference in retention ‐ end of treatment compared with treatment (low certainty).

2 findings from 1 review

Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users 2018 · Cochrane Headline outcomes only
RR 0.96 [0.87, 1.06]
1 study · 256 participants
Low
Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users 2018 · Cochrane Headline outcomes only
RR 0.93 [0.6, 1.43]
2 studies · 160 participants
Low

PFMT added to lifestyle intervention vs lifestyle intervention alone

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to bladder training vs bladder training alone

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

It is very uncertain whether PFMT added to bladder training changes number of women requiring further treatment such as surgery, drugs,… compared with bladder training alone (very low certainty).

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
RR 0.95 [0.57, 1.57]
1 study · 96 participants
Very low

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to magnetic stimulation vs magnetic stimulation alone

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to continence pessary vs continence pessary alone

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT prior to surgical intervention vs surgical intervention alone

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to HSGS vs HSGS alone

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PFMT added to vaginal cones vs vaginal cones alone

Number of women requiring further treatment such as surgery, drugs, mechanical devices (relapse) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review

Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
None of the studies reported on this outcome
0 studies
No studies found

Primary outcome: topical local anaesthetics vs placebo or no treatment

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental… 2014 · Cochrane All outcomes
None of the studies reported on this outcome
0 studies
No studies found