Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

67 questions · 68 findings · 6 reviews · Developmental, Psychosocial and Learning Problems

No studies found 16 · 23.5%GRADE not reported 10 · 14.7%Very low 14 · 20.6%Low 17 · 25%Moderate 10 · 14.7%High 1 · 1.5%

Probiotics vs placebo

Relief of pain · Children with recurrent abdominal pain

Probiotics probably leads to higher improvement in pain: 0 to 3 months' postintervention Different… compared with placebo (moderate certainty).

2 findings from 1 review

Probiotics vs placebo

Improvement in pain: 0 to 3 months' postintervention Subgroup (irritable bowel syndrome) Different measures were used to assess improvement in pain, as above. · Children with recurrent abdominal pain

Probiotics probably leads to higher improvement in pain: 0 to 3 months' postintervention Subgroup… compared with placebo (moderate certainty).

1 finding from 1 review

Fibre vs placebo

Improvement in pain: 0 to 3 months' postintervention Improvement in pain was defined and measured differently in the 2 included studies: using a "stomach ache diary" and the Faces Pain Scale (Bieri 1990). · Children with recurrent abdominal pain

Fibre showed no clear difference in improvement in pain: 0 to 3 months' postintervention Improvement in… compared with placebo (low certainty).

1 finding from 1 review