Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

99 questions · 116 findings · 18 reviews · Gut

No studies found 7 · 6%GRADE not reported 3 · 2.6%Very low 62 · 53.4%Low 25 · 21.6%Moderate 17 · 14.7%High 2 · 1.7%

Oral iron sulphate vs oral iron hydroxide polymaltose complex

Serious adverse events ‐ active or inactive disease (14 days) · IBD patients

It is very uncertain whether oral iron sulphate changes serious adverse events ‐ active or inactive disease (14 days) compared with oral iron hydroxide polymaltose complex (very low certainty).

1 finding from 1 review

Corticosteroids vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: corticosteroids changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

5‐ASA vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

Risk of postoperative infectious complications: 5‐ASA led to lower incisional infections and wound dehiscence within 30 days of surgery compared with control; GRADE not reported.

1 finding from 1 review

5‐ASA vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: 5‐ASA changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: immunomodulators vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: immunomodulators changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Intra‐abdominal infectious complications within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes intra‐abdominal infectious complications within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐TNF agents vs control

Extra‐abdominal infections within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐TNF agents changes extra‐abdominal infections within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Infectious complications · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes overall infectious complications within 30 days of surgery compared with control (very low certainty).

3 findings from 1 review

Risk of postoperative infectious complications: anti‐integrin agents vs control

Incisional infections and wound dehiscence within 30 days of surgery · people with inflammatory bowel disease

It is very uncertain whether risk of postoperative infectious complications: anti‐integrin agents changes incisional infections and wound dehiscence within 30 days of surgery compared with control (very low certainty).

1 finding from 1 review