Findings

What do systematic reviews say?

64 questions · 65 findings · 12 reviews

No studies found 4 · 6.2%GRADE not reported 6 · 9.2%Very low 13 · 20%Low 10 · 15.4%Moderate 24 · 36.9%High 8 · 12.3%

Participant‐reported sleep problems (scale: 0 to 28; higher scores indicate more sleep problems) · patients with fibromyalgia

1 finding from 1 review

Anticonvulsants for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 3139 participants
High

Withdrawals due to adverse events · patients with fibromyalgia

Pregabalin leads to higher withdrawal due to adverse events compared with placebo at end of treatment (high certainty).

1 finding from 1 review

Anticonvulsants for fibromyalgia 2013 · Cochrane Headline outcomes only
RR 1.68 [1.36, 2.07]
5 studies · 3259 participants
High

Serious adverse events · patients with fibromyalgia

Pregabalin showed no clear difference in serious adverse events compared with placebo at end of treatment (moderate certainty).

1 finding from 1 review

Anticonvulsants for fibromyalgia 2013 · Cochrane Headline outcomes only
RR 1.03 [0.71, 1.49]
4 studies · 2729 participants
Moderate

Dizziness · patients with fibromyalgia

Pregabalin leads to higher dizziness reported to be an adverse event compared with placebo at end of treatment (high certainty).

1 finding from 1 review

Anticonvulsants for fibromyalgia 2013 · Cochrane Headline outcomes only
RR 3.77 [3.06, 4.63]
5 studies · 3257 participants
High