Summary of findings: urate oxidase vs allopurinol
- Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer 2017 · Cochrane Headline outcomes onlyno estimate extracted1 study · 52 participantsLow
Summary of findings: urate oxidase may leads to higher frequency of adverse events ( compared with allopurinol (low certainty).
Benzbromarone showed no clear difference in acute gout attacks compared with allopurinol (low certainty).
Probenecid showed no clear difference in acute gout attacks compared with allopurinol (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Benzbromarone showed no clear difference in serum urate normalisation compared with allopurinol (moderate certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Benzbromarone showed no clear difference in withdrawal due to adverse events compared with allopurinol (low certainty).
Benzbromarone showed no clear difference in total adverse events compared with allopurinol (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Febuxostat 40 mg/day showed no clear difference in incidence of gout flares compared with allopurinol (high certainty).
Febuxostat 40 mg/day showed no clear difference in serum uric acid <6.0 mg/dL at final visit compared with allopurinol (moderate certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.