Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

123 questions · 130 findings · 7 reviews · Pain control and patient management

No studies found 63 · 48.5%GRADE not reported 18 · 13.8%Very low 43 · 33.1%Low 3 · 2.3%Moderate 3 · 2.3%High 0 · 0%

Infiltration injection local anaesthetic vs no treatment or placebo

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Lip or cheek biting, numbness or allergy · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Postoperative pain · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection local anaesthetic vs no treatment or placebo

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Intraligamental injection local anaesthetic vs no treatment

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Hypnosis vs Inhalation sedation with nitrous oxide and oxygen

Completion of treatment · Children aged 10 to 16 years undergoing orthodontic extractions (Braithwaite 2005)

The review found no eligible studies for this question.

1 finding from 1 review
  • Completion of treatment (yes/no) was a protocol-planned primary outcome but was not reported by the included study for this comparison (Braithwaite 2005); one participant in the sedation arm was withdrawn during…
    Studies not reported
    No studies found

Hypnosis vs Inhalation sedation with nitrous oxide and oxygen

Anxiety control and overall response to treatment during tooth extraction · Children aged 10 to 16 years undergoing orthodontic extractions (Braithwaite 2005)
1 finding from 1 review
  • Hypnosis did not provide sufficient anxiety control during tooth extraction, and overall response to treatment remained statistically lower than response to inhalation sedation with nitrous oxide and oxygen (i.e. the…
    1 study · 10 participants
    GRADE not reported

Hypnosis vs No hypnosis (no hypnotic intervention)

Completion of treatment · Children and adolescents (0 to 16 years) needing dental treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Completion of treatment was a protocol-planned primary outcome but was not reported as an outcome by any of the three included studies; statistical analysis and meta-analysis were not possible due to the insufficient…
    Studies not reported
    No studies found

Hypnosis vs No hypnosis (no hypnotic intervention)

Physiological measures during local anaesthesia (pulse rate and oxygen saturation) · Children aged 4 to 13 years with no previous dental experience undergoing restorative treatment with local anaesthesia (Gokli 1994)
1 finding from 1 review
  • With regard to oxygen saturation and pulse rate, only pulse rate was significantly lower in the hypnosis group (P = 0.005); oxygen saturation did not differ significantly. (Gokli 1994; cross-over, 29 children.)
    1 study · 29 participants
    GRADE not reported