Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

Supplementary feeding vs no food supplementation or placebo

Mean weight‐for‐age z‐score · Children aged less than five years in LMIC
2 findings from 1 review

Supplementary feeding vs no food supplementation or placebo

Mean height‐for‐age z‐score · Children aged less than five years in LMIC
2 findings from 1 review

Intermittent use of iron supplements vs placebo or no intervention

Anaemia · children under 12 years of age

Intermittent use of iron supplements probably leads to lower anaemia (haemoglobin below a cut‐off defined by trialists, taking… compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Engagement of community leaders vs usual care

Proportion of children who received the vaccine under study (measles) · children under 5 years of age

Engagement of community leaders probably leads to higher proportion of children who received the vaccine under study (measles) compared with routine care (moderate certainty).

1 finding from 1 review

Case management for integrated care vs usual care of older people living with frailty

All‐cause mortality · people aged 65 years and older living with frailty

Case management for integrated care showed no clear difference in mortality compared with usual care of older people living with frailty (low certainty).

1 finding from 1 review

Case management for integrated care vs usual care of older people living with frailty

Change in place of residence to a nursing or residential home · people aged 65 years and older living with frailty

Case management for integrated care showed no clear difference in change in place of residence to a nursing or residential home compared with usual care of older people living with frailty (low certainty).

1 finding from 1 review

Case management for integrated care vs usual care of older people living with frailty

Change in healthcare utilisation (hospital admissions) · people aged 65 years and older living with frailty

Case management for integrated care showed no clear difference in change in healthcare utilisation (hospital admissions) compared with usual care of older people living with frailty (moderate certainty).

1 finding from 1 review