Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

179 questions · 189 findings · 18 reviews · Headline outcomes only

No studies found 28 · 14.8%GRADE not reported 17 · 9%Very low 44 · 23.3%Low 53 · 28%Moderate 44 · 23.3%High 3 · 1.6%

Endometrial resection or ablation vs unspecified (or at surgeon's discretion) route of hysterectomy

Acceptability Proportion satisfied with treatment · heavy menstrual bleeding

Endometrial resection/ablation showed no clear difference in acceptability Proportion satisfied with treatment compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection or ablation vs unspecified (or at surgeon's discretion) route of hysterectomy

Safety Any serious adverse event · heavy menstrual bleeding

Endometrial resection/ablation probably leads to lower safety Any serious adverse event compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection or ablation vs open hysterectomy

Effectiveness Proportion of women with perception of improvement of bleeding symptoms · HMB

Endometrial resection or ablation probably leads to lower effectiveness Woman's perception (proportion with improvement in… compared with open hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection or ablation vs minimally invasive hysterectomy

Acceptability Proportion satisfied with treatment · heavy menstrual bleeding

Endometrial resection or ablation probably leads to lower acceptability Proportion satisfied with treatment compared with minimally invasive hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection or ablation vs minimally invasive hysterectomy

Requirement for further surgery for treatment failure within 1 year after surgery · heavy menstrual bleeding

Endometrial resection or ablation probably leads to higher requirement for further surgery for treatment failure within 1 year… compared with minimally invasive hysterectomy (moderate certainty).

1 finding from 1 review

Summary of findings: endovenous ablation and compression vs compression alone

Ulcer healing time (measured as days from randomisation and followed‐up to 1 year) · people with venous leg ulcers

Summary of findings: endovenous ablation and compression leads to higher ulcer healing time (measured as days from randomisation and… compared with compression alone (high certainty).

1 finding from 1 review

Summary of findings: endovenous ablation and compression vs compression alone

The proportion of pressure ulcers healed · people with venous leg ulcers

Summary of findings: endovenous ablation and compression showed no clear difference in proportion of ulcers healed at 90 days (90 days compared with compression alone (moderate certainty).

2 findings from 1 review