Ambulation · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
Decompressive surgery plus radiotherapy may leads to higher ambulation Immediately after completing RT compared with radiotherapy (low certainty).
1 finding from 1 review
Survival (short term) At 30 days · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
Decompressive surgery plus radiotherapy showed no clear difference in survival (short term) At 30 days compared with radiotherapy (low certainty).
1 finding from 1 review
Reduction in analgesic and narcotic use One month after radiation · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
1 finding from 1 review
Urinary continence 3 months after surgery MCID: 5% absolute difference · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
1 finding from 1 review
Local recurrence · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
1 finding from 1 review
Quality of life · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Cognitive function ‐ Wechsler Memory Scales WMS‐general memory score1 · Multiple sclerosis
1 finding from 1 review
Intervention not reported
Cognitive function ‐ Selective Reminding Test total SRT1 · Multiple sclerosis
1 finding from 1 review
Intervention not reported
Clinical global impression of change ‐ patient's self‐reported impression of memory change · Multiple sclerosis
The intervention showed no clear difference in clinical global impression of change ‐ patient's self‐reported… (high certainty).
1 finding from 1 review
Intervention not reported
Clinical global impression of change ‐ patient's self‐reported impression of cognitive change · Multiple sclerosis
The intervention showed no clear difference in clinical global impression of change ‐ patient's self‐reported… (high certainty).
1 finding from 1 review
Intervention not reported
Clinical global impression of change ‐ clinician's impression of memory change · Multiple sclerosis
The intervention showed no clear difference in clinical global impression of change ‐ clinician's impression of… (moderate certainty).
1 finding from 1 review
Intervention not reported
Clinical global impression of change ‐ clinician's impression of cognitive change · Multiple sclerosis
The intervention leads to higher clinical global impression of change ‐ clinician's impression of… (high certainty).
1 finding from 1 review
Intervention not reported
At least 50% reduction in pain · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review
Intervention not reported
At least 30% reduction in pain · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review
Intervention not reported
Proportion below 30/100 mm on VAS · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Patient Global Impression of Change very much improved (patient global evaluation of pain relief complete or good) · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review
Intervention not reported
Patient Global Impression of Change much or very much improved (patient global evaluation of pain relief complete, good or moderate) · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review
Intervention not reported
Any measure of 'substantial' pain relief · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
1 finding from 1 review
Intervention not reported
Adverse event withdrawals · neuropathic pain (6 studies in central neuropathic pain due to multiple sclerosis, spinal cord injury, polyneuropathy, central post‐stroke…
It is very uncertain whether the intervention changes adverse event withdrawals (very low certainty).
1 finding from 1 review