Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,036 questions · 1,100 findings · 261 reviews

No studies found 160 · 14.5%GRADE not reported 188 · 17.1%Very low 270 · 24.5%Low 303 · 27.5%Moderate 139 · 12.6%High 40 · 3.6%

Sildenafil vs placebo

Sexual function: Objective assessment (Global efficacy questionnaire, improved erections) · patients with sexual dysfunction due to antipsychotic drug therapy

ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL may leads to higher sexual function: Objective assessment (Global efficacy… compared with PLACEBO (low certainty).

1 finding from 1 review

IV + inhaled beta agonist vs inhaled beta‐agonist

Clinical Failure (children with a severe to moderate overall clinical assessment score at two hours) · patients with acute asthma

IV + inhaled beta agonist probably leads to lower clinical Failure (children with a severe to moderate overall… compared with inhaled beta‐agonist (moderate certainty).

1 finding from 1 review

Betamethasone oral mini-pulse therapy vs Topical triamcinolone acetonide paste

Investigator‐ or physician‐rated global assessment of disease severity · People with erosive oral lichen planus

Betamethasone oral mini-pulse therapy led to higher physician Global Assessment (clinical severity, 0-12 score) compared with topical triamcinolone acetonide 0.1% paste; GRADE not reported.

1 finding from 1 review