Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

841 questions · 868 findings · 102 reviews

No studies found 276 · 31.8%GRADE not reported 111 · 12.8%Very low 197 · 22.7%Low 187 · 21.5%Moderate 88 · 10.1%High 9 · 1%

Nano-silver fluoride vs Not specified

Arrest of dentine caries · Children with active dentine caries

One randomised trial found nano-silver fluoride arrested dentine caries without the black staining seen with silver diamine fluoride; ungraded.

1 finding from 1 review

30% silver diamine fluoride vs Not specified

Arrest of dentine caries · Children with active dentine caries in primary teeth

One study reported 30% silver diamine fluoride effectively arrested dentine caries in primary teeth; ungraded.

1 finding from 1 review

12% silver diamine fluoride (SDF), single (one-off) application vs Not specified

Arrest of dentine caries · Children with active dentine caries

One trial found a single application of 12% silver diamine fluoride did not arrest dentine caries; ungraded.

1 finding from 1 review

Open reduction and fixation vs Closed (conservative) management (no active intervention other than soft diet, analgesics or antibiotics; or intermaxillary/maxillary-mandibular fixation with rigid or elastic traction)

Outcome not reported · Adults, over 18 years of age, with unilateral or bilateral fractures of the mandibular condyles

The review found no eligible studies for this question.

1 finding from 1 review

Manipulation vs mobilisation

Acute, subacute and chronic neck pain Intermediate‐term · patients with acute, subacute and chronic neck pain

Manipulation showed no clear difference in acute, subacute and chronic neck pain Intermediate‐term compared with mobilisation (moderate certainty).

1 finding from 1 review

Manipulation (cervical) vs oral medicine

Acute and subacute neck pain Intermediate‐term · patients with acute and subacute neck pain

Manipulation (cervical) showed no clear difference in acute and subacute neck pain Intermediate‐term compared with oral medicine (moderate certainty).

1 finding from 1 review