Taste discrimination improvement · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
1 finding from 1 review
Taste acuity improvement - objective outcome (continuous) - individual taste sensations · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… showed no clear difference in taste acuity improvement - objective outcome (continuous) -… compared with placebo; GRADE not reported.
1 finding from 1 review
Interventions for managing taste disturbances 2017 · Cochrane All outcomesChronic renal failure
Results (Mahajan 1980, chronic renal failure; Analysis 1.3): mean difference by taste sensation - salt MD 285 (95% CI 238.75 to 331.25); sweet MD 190 (142.36 to 237.64); sour MD 10 (-16.43 to 36.43); bitter MD 2.40…
1 study · 22 participants
GRADE not reported
Taste acuity improvement - objective outcome (continuous) - taste detection (cross-over trial) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous) - taste… compared with placebo (very low certainty).
1 finding from 1 review
Taste acuity improvement - patient-reported outcome · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - patient-reported outcome compared with placebo (very low certainty).
1 finding from 1 review
Taste acuity improvement - objective outcome (continuous) - taste recognition (cross-over trial) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous) - taste… compared with placebo (very low certainty).
1 finding from 1 review
Health‐related quality of life · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
1 finding from 1 review
Taste acuity improvement - objective outcome (dichotomous) - chronic renal failure · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… led to higher taste acuity improvement - objective outcome (dichotomous) - chronic… compared with placebo; GRADE not reported.
1 finding from 1 review
Taste acuity improvement - objective outcome (continuous data) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous data) compared with placebo (very low certainty).
1 finding from 1 review
Adverse events · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
Taste acuity improvement - objective outcome (dichotomous data) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (dichotomous data) compared with placebo (very low certainty).
1 finding from 1 review
Percentage of bleeding on probing (BOP) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
It is very uncertain whether SPT performed by non-specialist clinicians (general dental… changes bleeding on probing (%) compared with SPT performed by specialists (specialist practice) (very low certainty).
1 finding from 1 review
Probing pocket depth · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
It is very uncertain whether SPT performed by non-specialist clinicians (general dental… changes probing pocket depth (mm) compared with SPT performed by specialists (specialist practice) (very low certainty).
1 finding from 1 review
Tooth loss · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
The review found no eligible studies for this question.
1 finding from 1 review
Not measured
0 studies
No studies found
Periodontitis (clinical attachment loss) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
The review found no eligible studies for this question.
1 finding from 1 review
Not measured
0 studies
No studies found
Adverse events · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
The review found no eligible studies for this question.
1 finding from 1 review
Not measured
0 studies
No studies found
Adverse effects · People with squamous cell carcinoma of the oral cavity or oropharynx
Non-specific immunotherapy (recombinant interleukin-2 or BCG cell… showed no clear difference in adverse effects compared with standard therapy alone; GRADE not reported.
9 findings from 1 review
RR 11.00 [0.67, 179.29]
1 study · 24 participants
GRADE not reported
RR 3.40 [0.15, 77.34]
1 study · 30 participants
GRADE not reported
RR 1.47 [0.75, 2.90]
1 study · 30 participants
GRADE not reported
Show 6 more findings
RR 0.57 [0.22, 1.50]
1 study · 30 participants
GRADE not reported
RR 0.67 [0.13, 3.30]
1 study · 24 participants
GRADE not reported
RR 0.38 [0.04, 3.26]
1 study · 30 participants
GRADE not reported
RR 1.24 [0.90, 1.70]
1 study · 30 participants
GRADE not reported
RR 1.71 [0.33, 8.83]
1 study · 30 participants
GRADE not reported
RR 5.00 [0.27, 94.34]
1 study · 24 participants
GRADE not reported
Disease-free survival · People with squamous cell carcinoma of the oral cavity or oropharynx
It is very uncertain whether non-specific immunotherapy (recombinant interleukin-2 or BCG cell… changes disease-free survival compared with standard therapy alone (very low certainty).
1 finding from 1 review
Overall survival · People with squamous cell carcinoma of the oral cavity or oropharynx
2 findings from 1 review
BCG-CWP + surgery versus surgery alone: 3-year overall survival 10/10 vs 9/10; too few participants to calculate a hazard ratio (Bier 1981, 24 participants).
1 study · 24 participants
GRADE not reported
HR 0.52 [0.31, 0.87]
1 study · 201 participants
Very low
Locoregional control · People with squamous cell carcinoma of the oral cavity or oropharynx
1 finding from 1 review
Self-efficacy related to oral health · school‐age children and adolescents
Theory-based educational interventions significantly improved oral health self-efficacy (SMD 1.49; low certainty), though between-study heterogeneity was very high.
1 finding from 1 review