Worse or unimproved within 5 weeks from randomisation · multiple sclerosis patients with acute exacerbations
Corticosteroids or ACTH probably leads to lower worse or unimproved within 5 weeks from randomisation compared with placebo (moderate certainty).
1 finding from 1 review
Mean disability (EDSS) score—at 1 week after randomisation · multiple sclerosis patients with acute exacerbations
Corticosteroids or ACTH showed no clear difference in mean disability (EDSS) score—at 1 week after randomisation compared with placebo (moderate certainty).
1 finding from 1 review
Participants with new exacerbations during · multiple sclerosis patients with acute exacerbations
It is very uncertain whether corticosteroids or ACTH changes participants with new exacerbations during compared with placebo (very low certainty).
1 finding from 1 review
Oral health-related quality of life · Persons with disabilities (children and adults with autism, Down syndrome, cerebral palsy, hearing impairment, or multiple disabilities)…
Persons with disabilities in Saudi Arabia report poorer overall oral health-related quality of life and greater oral-health impact than those without disabilities, synthesized narratively without a pooled estimate (ungraded).
1 finding from 1 review
Dental caries prevalence and severity · Persons with disabilities (children and adults with autism, Down syndrome, cerebral palsy, hearing impairment, or multiple disabilities)…
Dental caries prevalence and severity are high among persons with disabilities in Saudi Arabia (60% to over 80%), and the one comparative autism study reported significantly higher caries than controls; synthesized narratively (ungraded).
1 finding from 1 review
Narrative synthesis (no pooled estimate). High dental caries burden among PWDs: caries prevalence 60% to over 80% (abstract). Alkahtani 2019 (hearing-impaired adults, single-arm): caries prevalence 82.2%, treatment…
Studies not reported
GRADE not reported
Moderate gingival inflammation / gingival health · Persons with disabilities (children and adults with autism, Down syndrome, cerebral palsy, hearing impairment, or multiple disabilities)…
Gingival inflammation is common among persons with disabilities in Saudi Arabia (moderate-to-severe up to about 60%), reported narratively without a pooled comparative estimate (ungraded).
1 finding from 1 review
Intervention not reported
Total studies: 50 Total participants: 14,926 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
50 participants
GRADE not reported
Intervention not reported
Duloxetine high dose RCTs: 14 Participants: 3683 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
14 participants
Low
Intervention not reported
Duloxetine standard dose RCTs: 18 Participants: 4959 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
18 participants
Moderate
Intervention not reported
Milnacipran high dose RCTs: 2 Participants: 1670 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
2 participants
Low
Intervention not reported
Milnacipran standard dose RCTs: 4 Participants: 1866 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
4 participants
Moderate
Intervention not reported
Duloxetine low dose RCTs: 6 Participants: 1104 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
6 participants
Moderate
Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review
Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
It is very uncertain whether ARP with demineralised bone matrix, single particle size changes changes in vertical height of alveolar ridge (mm) compared with ARP with demineralised bone matrix, multiple particle size (very low certainty).
1 finding from 1 review
Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
The review found no eligible studies for this question.
1 finding from 1 review
Outcome not reported
0 studies
No studies found
Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
The review found no eligible studies for this question.
1 finding from 1 review
Outcome not reported
0 studies
No studies found
Cost‐effectiveness · long‐term bladder management
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants with symptomatic UTI · long‐term bladder management
Single‐use (sterile) catheter showed no clear difference in number with symptomatic UTI1 compared with multiple‐use (clean) catheter (low certainty).
1 finding from 1 review
Participant‐assessed outcome(satisfaction) · long‐term bladder management
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant‐assessed outcome(preference) · long‐term bladder management
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found