Healing of osteonecrosis - healed ('healed' vs 'improved', 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - healed ('healed' vs 'improved',… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.56 [0.77, 3.18]
1 study · 46 participants
GRADE not reported
RR 1.00 [0.25, 4.00]
1 study · 18 participants
GRADE not reported
RR 0.95 [0.44, 2.04]
1 study · 40 participants
GRADE not reported
Show 2 more findings
Pain · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Quality of life · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Cure: short‐term success · patients on maintenance HD with CRBSI
It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: short‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).
1 finding from 1 review
RR 0.92 [0.74, 1.15]
18 participants
Very low
Cure: long‐term success · patients on maintenance HD with CRBSI
It is very uncertain whether systemic antibiotics plus antibiotic lock solutions plus tissue… changes cure: long‐term success compared with systemic antibiotics plus antibiotic lock solutions plus heparin (very low certainty).
1 finding from 1 review
RR 64 [0.38, 1.06]
18 participants
Very low
Cure: infection‐free survival · patients on maintenance HD with CRBSI
1 finding from 1 review
no estimate extracted
18 participants
Very low
Stenosis or thrombosis of vascular access site after catheter removal · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · patients on maintenance HD with CRBSI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis
Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing attachment level (PAL) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported.
1 finding from 1 review
Recurrence of peri-implantitis · People with at least one dental implant affected by perimplantitis
1 finding from 1 review
Implant failure · People with at least one dental implant affected by perimplantitis
1 finding from 1 review
Complications and side effects · People with at least one dental implant affected by perimplantitis
1 finding from 1 review
Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis
Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing pocket depth (PPD) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported.
1 finding from 1 review
All‐cause mortality · febrile neutropenia
Early discontinuation of antibiotic treatment showed no clear difference in mortality compared with treatment until neutropenia resolution (low certainty).
1 finding from 1 review
Clinical failure · febrile neutropenia
It is very uncertain whether early discontinuation of antibiotic treatment changes clinical failure compared with treatment until neutropenia resolution (very low certainty).
1 finding from 1 review
Bacteraemia · febrile neutropenia
It is very uncertain whether early discontinuation of antibiotic treatment changes any bacteraemia compared with treatment until neutropenia resolution (very low certainty).
1 finding from 1 review
Overall mortality · people with cancer who have febrile neutropenia
Mortality with anti‐gram‐positive antibiotics showed no clear difference in overall mortality compared with placebo (moderate certainty).
1 finding from 1 review
Resolution of VUR · primary VUR
Antibiotic prophylaxis showed no clear difference in resolution of VUR after 1 to 2 years: unit of analysis (children) compared with surveillance or no treatment (low certainty).
1 finding from 1 review