Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,209 questions · 2,322 findings · 227 reviews · Headline outcomes only

No studies found 644 · 27.7%GRADE not reported 135 · 5.8%Very low 591 · 25.5%Low 582 · 25.1%Moderate 309 · 13.3%High 61 · 2.6%

Electrical stimulation vs Placebo / sham solution

Participants with improvement in urgency urinary incontinence · Adults with overactive bladder (OAB)

Electrical stimulation showed no clear difference in participants with improvement in urgency urinary incontinence compared with placebo or sham treatment (low certainty).

1 finding from 1 review

Manipulation (thoracic) vs inactive control

Acute and subacute neck pain Short‐term · patients with acute, subacute and chronic neck pain

Manipulation (thoracic) showed no clear difference in acute and subacute neck pain Short‐term compared with inactive control (moderate certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) may leads to higher UCVA of 20/20 or better compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Eyes within ± 0.5 D of target refraction · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) showed no clear difference in within 0.50 D of target refraction compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Lost one or more lines of BCVA · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) showed no clear difference in lost one or more lines of BCVA compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Final BCVA of 20/40 or less · patients with myopia

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) changes final BCVA of 20/40 or less compared with photorefractive keratectomy (PRK) (very low certainty).

1 finding from 1 review