It is very uncertain whether ursodeoxycholic acid (UDCA) changes stillbirth compared with placebo (very low certainty).
It is very uncertain whether ursodeoxycholic acid (UDCA) changes fetal distress/asphyxial events compared with placebo (very low certainty).
Neonatal and child outcomes: corticosteroids leads to lower perinatal death (composite of fetal death (in utero death) and… compared with placebo or no treatment (high certainty).
Neonatal and child outcomes: corticosteroids leads to lower neonatal death (infants born with signs of life who die within the… compared with placebo or no treatment (high certainty).
Neonatal and child outcomes: corticosteroids leads to lower respiratory distress syndrome№ of participants: 11,183(26 RCTs) compared with placebo or no treatment (high certainty).
Neonatal and child outcomes: corticosteroids probably leads to lower intraventricular haemorrhage (IVH)№ of participants: 8475(12 RCTs) compared with placebo or no treatment (moderate certainty).
Neonatal and child outcomes: corticosteroids probably leads to lower developmental delay in childhood№ of participants: 600 (3 RCTs). Age… compared with placebo or no treatment (moderate certainty).
Maternal outcomes: corticosteroids showed no clear difference in maternal death compared with placebo or no treatment (moderate certainty).
Maternal outcomes: corticosteroids showed no clear difference in chorioamnionitis№ of participants: 8374(15 RCTs) compared with placebo or no treatment (moderate certainty).
Maternal outcomes: corticosteroids showed no clear difference in endometritis№ of participants: 6764(10 RCTs) compared with placebo or no treatment (moderate certainty).
It is very uncertain whether oral magnesium changes composite outcome: symptoms of leg cramps (intensity and frequency)… compared with placebo/no treatment (very low certainty).
Oral magnesium showed no clear difference in side effects ‐ nausea compared with placebo/no treatment (low certainty).
Oral magnesium showed no clear difference in side effects ‐ diarrhoea compared with placebo/no treatment (low certainty).
Oral magnesium showed no clear difference in side effects ‐ any compared with placebo/no treatment (low certainty).
It is very uncertain whether oral calcium changes frequency of leg cramps after treatment: never compared with no treatment (very low certainty).
It is very uncertain whether oral calcium changes frequency of leg cramps after treatment: never compared with oral vitamin C (very low certainty).
Oral magnesium may leads to higher frequency of leg cramps after treatment: never compared with placebo/no treatment (low certainty).