Oral health-related quality of life · Children with dental caries
SDF plus fluoride varnish did not significantly differ from ART plus fluoride varnish for oral health-related quality of life (MD 0.16, 95% CI -0.1 to 0.42; ungraded).
1 finding from 1 review
Immediate bond strength (MPa) · Dental adhesives bonded to caries-affected dentin (in vitro)
Prior SDF followed by a rinsing step significantly increases adhesive bond strength to caries-affected dentin (MD -4.79 MPa favoring SDF, 95% CI -9.19 to -0.40; ungraded).
1 finding from 1 review
Immediate bond strength (MPa) · Dental adhesives bonded to caries-affected dentin (in vitro)
Only one study assessed SDF without a rinsing step on adhesive bonding to caries-affected dentin (Kucukyilmaz 2016, which reported impaired bond strength); no meta-analysis was possible, so no pooled estimate is available.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found no difference in pulpotomy success between MTA and platelet-rich fibrin (both 100% through 24 months; not pooled; ungraded).
1 finding from 1 review
Single RCT (Keswani 2014, 62 teeth): 100% clinical and radiographic success in both MTA and PRF at 6, 12 and 24 months (MTA 29/29, 27/27, 26/26; PRF 30/30, 29/29, 27/27); no difference between groups; not pooled
1 study · 62 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
MTA and calcium hydroxide had similar clinical and radiographic pulpotomy success at 6 months (RR 1.00, 95% CI 0.94 to 1.06; 2 RCTs; ungraded).
2 findings from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found no difference in pulpotomy success between MTA and calcium-enriched mixture (both 100% at 6 and 12 months; not pooled; ungraded).
1 finding from 1 review
Single RCT (Nosrat 2012, 118 roots): 100% clinical and radiographic success in both MTA and CEM at 6 and 12 months (MTA 53/53 then 54/54 roots; CEM 55/55 then 57/57 roots); no statistical difference between groups at…
1 study · 118 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found higher pulpotomy success with triple antibiotic paste than abscess remedy (100% vs 80%; statistically significant, P<0.05; not pooled; ungraded).
1 finding from 1 review
Single RCT (Eppa 2018, 3-arm; 20 TAP and 20 AR teeth): TAP 100% (20/20) vs abscess remedy 80% (16/20) clinical and radiographic success; difference statistically significant at 3, 6, 9, 12, 18 and 24 months (P<0.05);…
1 study · 40 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found higher pulpotomy success with MTA than abscess remedy (100% vs 80%; statistically significant, P<0.05; not pooled; ungraded).
1 finding from 1 review
Single RCT (Eppa 2018, 3-arm; 20 MTA and 20 AR teeth): MTA 100% (20/20) vs abscess remedy 80% (16/20) clinical and radiographic success; the 4 abscess-remedy failures occurred at 3 months; difference statistically…
1 study · 40 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single 3-arm RCT found no difference in pulpotomy success between MTA and triple antibiotic paste (both 100%; not pooled; ungraded).
1 finding from 1 review
Single RCT (Eppa 2018, 3-arm; 20 MTA and 20 TAP teeth): 100% clinical and radiographic success in both MTA and TAP at all follow-ups (1-24 months); no difference between groups; not pooled
1 study · 40 participants
GRADE not reported
Amalgam: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · Dentists managing a defective direct amalgam restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective amalgam restoration with disruption of occlusal integrity, surveyed dentists most often preferred replacement over repair (pooled RR 1.70; p < 0.001); ungraded.
1 finding from 1 review
Amalgam: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · Dentists managing a defective direct amalgam restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
Subgroup (Continent: South America): pooled preference was replacement over repair for a defective amalgam restoration with partial loss or fracture of the restoration (RR 6.20); significant continental variation, p = 0.04.
9 findings from 1 review
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · Continent: South America
RR 6.20 [4.66, 8.25]
2 studies · 349 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · Continent: Europe
RR 2.61 [1.54, 4.42]
6 studies · 1075 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · Continent: Africa
RR 4.86 [3.79, 6.23]
2 studies · 339 participants
GRADE not reported
Show 6 more findings
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · HDI: High
RR 5.06 [4.22, 6.06]
7 studies · 1223 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · HDI: Low
RR 3.39 [2.18, 5.27]
2 studies · 350 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · Continent: Asia
RR 4.38 [2.91, 6.61]
11 studies · 1917 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · Overall (all 21 countries pooled)
RR 3.94 [2.93, 5.31]
21 studies · 3680 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · HDI: Medium
RR 7.13 [4.90, 10.35]
2 studies · 353 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · HDI: Very high
RR 2.99 [1.91, 4.67]
10 studies · 1754 participants
GRADE not reported
Composite: Preference for replacement over repair - Scenario 4: marginal discoloration · Dentists managing a defective direct resin composite restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective composite restoration with marginal discoloration, surveyed dentists most often preferred replacement over repair (pooled RR 1.97; p < 0.001); ungraded.
1 finding from 1 review
Composite: Preference for replacement over repair - Scenario 5: open margin · Dentists managing a defective direct resin composite restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective composite restoration with open margin, surveyed dentists most often preferred replacement over repair (pooled RR 3.93; p < 0.001); ungraded.
1 finding from 1 review
Amalgam: Preference for replacement over repair - Scenario 6: corrosion · Dentists managing a defective direct amalgam restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective amalgam restoration with corrosion, surveyed dentists most often preferred replacement over repair (pooled RR 1.59; p < 0.001); ungraded.
1 finding from 1 review
Amalgam: Preference for replacement over repair - Scenario 4: marginal discoloration · Dentists managing a defective direct amalgam restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
Subgroup (HDI: Very high): pooled preference was replacement over repair for a defective amalgam restoration with marginal discoloration (RR 6.48); significant HDI variation, p = 0.01.
5 findings from 1 review
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · HDI: Very high
RR 6.48 [3.71, 11.31]
10 studies · 1754 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · HDI: High
RR 7.06 [5.14, 9.69]
7 studies · 1223 participants
GRADE not reported
Clinical Decision-Making of Repair vs. Replacement of Defective Direct Dental Restorations: A Multinational… 2025 All outcomesNot applicable (single time-point survey, June to October 2023) · Multinational (21 countries across Africa, Asia, Europe, South America); general dental practice · HDI: Low
RR 3.58 [2.74, 4.69]
2 studies · 350 participants
GRADE not reported
Show 2 more findings
Composite: Preference for replacement over repair - Scenario 1: partial loss or fracture of the restoration · Dentists managing a defective direct resin composite restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective composite restoration with partial loss or fracture of the restoration, surveyed dentists most often preferred repair over replacement (pooled RR 0.72; p = 0.002); ungraded.
1 finding from 1 review
Composite: Preference for replacement over repair - Scenario 8: disruption of occlusal integrity · Dentists managing a defective direct resin composite restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective composite restoration with disruption of occlusal integrity, surveyed dentists most often preferred repair over replacement (pooled RR 0.37; p < 0.001); ungraded.
1 finding from 1 review
Amalgam: Preference for replacement over repair - Scenario 5: open margin · Dentists managing a defective direct amalgam restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective amalgam restoration with open margin, surveyed dentists most often preferred replacement over repair (pooled RR 5.14; p < 0.001); ungraded.
1 finding from 1 review
Composite: Preference for replacement over repair - Scenario 6: superficial discoloration · Dentists managing a defective direct resin composite restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective composite restoration with superficial discoloration, surveyed dentists most often preferred repair over replacement (pooled RR 0.28; p < 0.001); ungraded.
1 finding from 1 review
Amalgam: Preference for replacement over repair - Scenario 7: non-stable (mobile) restoration · Dentists managing a defective direct amalgam restoration (posterior occlusal Class I; standardized vignette of a 30-year-old,…
For a defective amalgam restoration with non-stable (mobile) restoration, surveyed dentists most often preferred replacement over repair (pooled RR 24.22; p < 0.001); ungraded.
1 finding from 1 review