Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

957 questions · 979 findings · 250 reviews

No studies found 159 · 16.2%GRADE not reported 75 · 7.7%Very low 264 · 27%Low 303 · 30.9%Moderate 138 · 14.1%High 40 · 4.1%

Sildenafil vs placebo

Sexual function: Objective assessment (Global efficacy questionnaire, improved erections) · patients with sexual dysfunction due to antipsychotic drug therapy

ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL may leads to higher sexual function: Objective assessment (Global efficacy… compared with PLACEBO (low certainty).

1 finding from 1 review

IV + inhaled beta agonist vs inhaled beta‐agonist

Clinical Failure (children with a severe to moderate overall clinical assessment score at two hours) · patients with acute asthma

IV + inhaled beta agonist probably leads to lower clinical Failure (children with a severe to moderate overall… compared with inhaled beta‐agonist (moderate certainty).

1 finding from 1 review

Betamethasone oral mini-pulse therapy vs Topical triamcinolone acetonide paste

Investigator‐ or physician‐rated global assessment of disease severity · People with erosive oral lichen planus

Betamethasone oral mini-pulse therapy led to higher physician Global Assessment (clinical severity, 0-12 score) compared with topical triamcinolone acetonide 0.1% paste; GRADE not reported.

1 finding from 1 review

Clobetasol-17-propionate 0.025% lipid-loaded microspheres vs Clobetasol propionate 0.025% ointment

Physician Global Assessment (Thongprasom score) · People with erosive oral lichen planus

Clobetasol-17-propionate 0.025% lipid-loaded microspheres showed no clear difference in physician Global Assessment (Thongprasom score) compared with conventional 0.025% clobetasol lipophilic ointment in hydrophilic…; GRADE not reported.

1 finding from 1 review

Artificial bone graft: InFuse (collagen matrix) impregnated with rhBMP-2 vs Traditional iliac crest cancellous bone graft

Clinical assessment: alveolar ridge healing (0 to 3 grading scale) · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)

Artificial bone graft: InFuse (collagen matrix) impregnated with… led to higher clinical assessment: alveolar ridge healing (0 to 3 grading scale) compared with traditional iliac crest cancellous bone graft; GRADE not reported.

1 finding from 1 review