Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

General life satisfaction Quality of Life Interview section, scale of 1 to 7 · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

It is very uncertain whether non‐integrated models of care ‐ Assertive community treatment… changes leaving the study early: Lost to treatment compared with standard care (very low certainty).

1 finding from 1 review

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Adverse event: Death ‐ not measured · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

CBT vs TAU

Reduction in pain intensity · chronic pain (excluding headache) in adults

It is very uncertain whether CBT changes pain intensity (number of people with ≥ 30 % improvement)… compared with TAU (at follow‐up) (very low certainty).

2 findings from 2 reviews · compare the 2 reviews

Summary of findings table ‐ Midwife continuity models vs other models of care

Admission to neonatal special care unit or intensive care unit · childbearing women and their infants (all) (important/secondary outcomes)

Summary of findings table ‐ Midwife continuity models showed no clear difference in admission to special care nursery/neonatal intensive care unit compared with other models of care (moderate certainty).

1 finding from 1 review

Ibuprofen vs morphine

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · children with acute postoperative pain

The review found no eligible studies for this question.

2 findings from 1 review

Ibuprofen vs ketorolac

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · children with acute postoperative pain

The review found no eligible studies for this question.

2 findings from 1 review