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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,112 questions in 171 reviews · Eyes and Vision
current versionsNo studies 587 · 27.8%Ungraded 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Brimonidine vs apraclonidine IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Brimonidine vs apraclonidine Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Brimonidine vs apraclonidine Adverse events ‐ during study period · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Apraclonidine vs pilocarpine IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Apraclonidine vs pilocarpine IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Apraclonidine vs pilocarpine Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | 2 studies · 277 participants | Moderate |
Apraclonidine vs pilocarpine IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | Low |
Apraclonidine vs pilocarpine IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | RR 0.87 [0.14, 5.63] | 2 studies · 390 participants | Low |
Medication vs placebo IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | RR 0.05 [0.01, 0.2] | 4 studies · 446 participants | Moderate |
Apraclonidine vs pilocarpine Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | 2 studies · 277 participants | Low |
Apraclonidine vs pilocarpine Adverse events ‐ during study period · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Medication given before LTP vs the same medication given after LTP IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Medication given before LTP vs the same medication given after LTP IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Medication given before LTP vs the same medication given after LTP Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Medication given before LTP vs the same medication given after LTP IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | RR 0.82 [0.25, 2.63] | 4 studies · 319 participants | Moderate |
Medication given before LTP vs the same medication given after LTP IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | RR 1.55 [0.19, 12.43] | 4 studies · 319 participants | Very low |
Medication given before LTP vs the same medication given after LTP Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | 3 studies · 198 participants | Moderate |
Medication given before LTP vs the same medication given after LTP Adverse events ‐ during study period · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Medication vs placebo Mean change in IOP from pre‐LTP within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | 4 studies · 151 participants | Moderate |
Medication vs placebo IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | RR 0.17 [0.09, 0.31] | 5 studies · 634 participants | Low |
Medication vs placebo IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | RR 0.22 [0.11, 0.42] | 9 studies · 817 participants | Very low |
Medication vs placebo Mean change in IOP from pre‐LTP between 2 and 24 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | 4 studies · 151 participants | Moderate |
Medication vs placebo Adverse events ‐ conjunctival blanching during study period · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | 2 studies · 319 participants | Moderate |
Brimonidine vs apraclonidine IOP increase of ≥ 5 mmHg within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | RR 2.28 [0.32, 16.03] | 2 studies · 71 participants | Very low |
Brimonidine vs apraclonidine IOP increase of ≥ 10 mmHg within 2 hours · people with glaucoma receiving LTP Perioperative medications for preventing temporarily increased intraocular pressure after laser… (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics Resolution of hordeolum at short term · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | RR 3.6 [1.34, 9.7] | 1 study · 32 participants | Low |
Acupuncture vs topical antibiotics plus warm compresses Participants who required surgical incision and drainage after the treatment period or seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics plus warm compresses Participants experiencing the occurrence of a chalazion after the treatment period or seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics plus warm compresses Participants experiencing the recurrence of a hordeolum within six months and one year · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics plus warm compresses Participants with a secondary hordeolum during or after the treatment period and seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics plus warm compresses Adverse effects · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs oral antibiotics plus warm compresses Resolution of hordeolum at short term · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | RR 1.45 [1.18, 1.78] | 1 study · 120 participants | Low |
Acupuncture vs oral antibiotics plus warm compresses Resolution of hordeolum between 8 and 30 days after diagnosis, or that closest to 14 days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs oral antibiotics plus warm compresses Participants who required surgical incision and drainage after the treatment period or seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs oral antibiotics plus warm compresses Participants experiencing the occurrence of a chalazion after the treatment period or seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs oral antibiotics plus warm compresses Participants experiencing the recurrence of a hordeolum within six months and one year · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics Resolution of hordeolum between 8 and 30 days after diagnosis, or that closest to 14 days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs oral antibiotics plus warm compresses Participants with a secondary hordeolum during or after the treatment period and seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs oral antibiotics plus warm compresses Adverse effects · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture plus conventional treatments vs conventional treatments alone Resolution of hordeolum at short term · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | RR 1.12 [1.03, 1.23] | 2 studies · 210 participants | Low |
Acupuncture plus conventional treatments vs conventional treatments alone Resolution of hordeolum between 8 and 30 days after diagnosis, or that closest to 14 days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture plus conventional treatments vs conventional treatments alone Participants who required surgical incision and drainage after the treatment period or seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture plus conventional treatments vs conventional treatments alone Participants experiencing the occurrence of a chalazion after the treatment period or seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture plus conventional treatments vs conventional treatments alone Participants experiencing the recurrence of a hordeolum within six months and one year · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture plus conventional treatments vs conventional treatments alone Participants with a secondary hordeolum during or after the treatment period and seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture plus conventional treatments vs conventional treatments alone Adverse effects · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | 1 participants | Ungraded |
Acupuncture vs topical antibiotics Participants who required surgical incision and drainage after the treatment period or seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics Participants experiencing the occurrence of a chalazion after the treatment period or seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics Participants experiencing the recurrence of a hordeolum within six months and one year · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |
Acupuncture vs topical antibiotics Participants with a secondary hordeolum during or after the treatment period and seven days after diagnosis · people with acute hordeolum Acupuncture for acute hordeolum (2017) · Cochrane | no estimate extracted | NR | No studies |