Adverse effects · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
It is very uncertain whether vitamin C 1400 mg plus vitamin E 800 mg changes adverse effects compared with placebo (very low certainty).
1 finding from 1 review
Frequency of hospitalization · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acute chest syndrome ( · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
It is very uncertain whether vitamin C 1400 mg plus vitamin E 800 mg changes frequency of sickle cell‐related complications: acute chest syndrome compared with placebo (very low certainty).
1 finding from 1 review
Haemoglobin status · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
1 finding from 1 review
Frequency of crisis · people with sickle cell disease
Zinc showed no clear difference in frequency of crisis compared with placebo (low certainty).
1 finding from 1 review
Severity of pain · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Severity of PTSD symptoms ‐ Clinician‐rated · adults experiencing acute traumatic stress symptoms
1 finding from 1 review
Quality of life at 3 months · adults experiencing acute traumatic stress symptoms
1 finding from 1 review
Dropouts due to adverse events · adults experiencing acute traumatic stress symptoms
1 finding from 1 review
PTSD rate at 3 months · adults experiencing acute traumatic stress symptoms
It is very uncertain whether escitalopram changes PTSD rate at 3 months compared with placebo (very low certainty).
1 finding from 1 review
Functional disability at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Severity of PTSD symptoms ‐ Clinician‐rated · adults experiencing acute traumatic stress symptoms
1 finding from 1 review
Dropouts due to adverse events · adults experiencing acute traumatic stress symptoms
Hydrocortisone showed no clear difference in dropouts due to adverse events at 3 months compared with placebo (low certainty).
1 finding from 1 review
PTSD rate at 3 months · adults experiencing acute traumatic stress symptoms
It is very uncertain whether hydrocortisone changes PTSD rate at 3 months compared with placebo (very low certainty).
1 finding from 1 review
Functional disability at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Rates of block‐related adverse events · adults undergoing surgery with general anaesthesia
Summary of findings ‐ Erector spinae plane block showed no clear difference in rates of block‐related adverse events compared with placebo block (low certainty).
1 finding from 1 review
Maternal anaemia · pregnant women
It is very uncertain whether summary of findings table ‐ Vitamin B12 supplementation changes maternal anaemia compared with placebo/no vitamin B12 supplementation (very low certainty).
1 finding from 1 review
Maternal vitamin B12 deficiency · pregnant women
It is very uncertain whether summary of findings table ‐ Vitamin B12 supplementation changes maternal vitamin B12 deficiency compared with placebo/no vitamin B12 supplementation (very low certainty).
1 finding from 1 review