Hydrocortisone vs placebo: Dropouts due to adverse events
- Population
- adults experiencing acute traumatic stress symptoms
- Intervention
- Hydrocortisone
- Comparison
- placebo
- Outcome
- Dropouts due to adverse events
Hydrocortisone showed no clear difference in dropouts due to adverse events at 3 months compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Hydrocortisone vs placebo Dropouts due to adverse events at 3 months · adults experiencing acute traumatic stress symptoms Hydrocortisone showed no clear difference in dropouts due to adverse events at 3 months compared with placebo (low certainty). Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… (2024) · Cochrane Headline outcomes only | RR 3.19 [0.13, 75.43] | 2 studies · 182 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals experiencing acute traumatic… 2024 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Hydrocortisone vs placebo · adults (aged 18 and older) exposed to a traumatic event · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.