Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

807 questions · 849 findings · 68 reviews · Headline outcomes only

No studies found 236 · 27.8%GRADE not reported 50 · 5.9%Very low 266 · 31.3%Low 168 · 19.8%Moderate 104 · 12.2%High 25 · 2.9%

Intervention not reported

Any upper gastrointestinal bleeding in infants at risk of upper gastrointestinal bleeding · newborn infants at risk of gastrointestinal bleeding

The intervention probably leads to lower any upper gastrointestinal bleeding in infants at risk of upper… (moderate certainty).

1 finding from 1 review

Methylphenidate vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Conners' Abbreviated Teacher Rating Scale, Conners' Abbreviated Parent Rating Scale, IOWA Conners' Teacher Rating Scale, Conners' Continuous Performance Task, Child Behaviour Ch... · children with ADHD and comorbid tic disorders
1 finding from 1 review

Methylphenidate vs placebo

Tic severity Measured by standardized rating scales: Yale Global Tic Severity Scale, Tourette Syndrome Severity Scale, Global Tic Rating Scale, Tic Symptom Self‐Report, Hopkins Motor/Vocal Scale · children with ADHD and comorbid tic disorders
1 finding from 1 review

Clonidine vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Conners' Abbreviated Teacher Rating Scale, Conners' Abbreviated Parent Rating Scale, IOWA Conners' Teacher Rating Scale, Conners' Continuous Performance Task, Child Behaviour Ch... · children with ADHD and comorbid tic disorders
1 finding from 1 review

Desipramine (antidepressant) vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Child Behaviour Checklist, Gordon Diagnostic System, Clinical Evaluation of Language Function, Matching Familial Figures Test, Porteus Maze Test, Restricted Academic Test, ADHD ... · children with ADHD and comorbid tic disorders
1 finding from 1 review

Desipramine (antidepressant) vs placebo

Tic severity Measured by standardized rating scales: Yale Global Tic Severity Scale, Tourette Syndrome Severity Scale, Hopkins Motor/Vocal Scale; ADHD Parent Linear Analogue Scale · children with ADHD and comorbid tic disorders
1 finding from 1 review