Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,166 questions · 1,249 findings · 76 reviews

No studies found 378 · 30.3%GRADE not reported 61 · 4.9%Very low 377 · 30.2%Low 284 · 22.7%Moderate 120 · 9.6%High 29 · 2.3%

Recombinant human growth hormone vs placebo or no intervention

Measures of mineral metabolism: change in serum phosphate mmol/L · children with X‐linked hypophosphataemia

It is very uncertain whether summary of findings ‐ recombinant growth hormone changes measures of mineral metabolism: change in serum phosphate mmol/L compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Recombinant human growth hormone vs placebo or no intervention

Measures of renal function: change in TmP/GFR · children with X‐linked hypophosphataemia

It is very uncertain whether summary of findings ‐ recombinant growth hormone changes measures of renal function: change in TmP/GFR compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Recombinant human growth hormone vs placebo or no intervention

Body proportions: sitting height SDS · children with X‐linked hypophosphataemia

Summary of findings ‐ recombinant growth hormone showed no clear difference in body proportions: sitting height SDS compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Protein vs standard diet

Gastrointestinal adverse events · patients (> 65 years) following hip fracture; patients with a recent stroke

It is very uncertain whether summary of findings table ‐ Protein changes side effects: at least one adverse gastrointestinal event compared with standard diet (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Collagen vs standard diet or placebo

Adverse effects/events: at least 1 adverse effect ‐ as defined by individual studies. · adults with pressure ulcers

It is very uncertain whether summary of findings table ‐ Collagen changes side effects: at least one adverse event compared with standard diet or placebo (very low certainty).

1 finding from 1 review