Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

801 questions · 875 findings · 91 reviews

No studies found 182 · 20.8%GRADE not reported 220 · 25.1%Very low 229 · 26.2%Low 128 · 14.6%Moderate 76 · 8.7%High 40 · 4.6%

Interdental brushing plus toothbrushing vs Flossing plus toothbrushing

Plaque · Adults, 16 years and older (dentate)

Interdental brushing plus toothbrushing showed no clear difference in plaque (plaque indices; standardised across indices) compared with flossing plus toothbrushing (low certainty).

2 findings from 1 review · compare the 2 reviews

Visual screening (oral visual inspection) by trained health workers vs No screening

Oral cancer incidence · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…

Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer incidence compared with no screening; GRADE not reported.

2 findings from 1 review

Interdental brushing plus toothbrushing vs Toothbrushing alone

Gingivitis · Adults, 16 years and older (dentate)

It is very uncertain whether interdental brushing plus toothbrushing changes gingivitis (Loe-Silness gingival index, interproximal; scale 0 to 4) compared with toothbrushing alone (very low certainty).

1 finding from 1 review · compare the 2 reviews

Visual screening (oral visual inspection) by trained health workers vs No screening

Quality of life · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…

The review found no eligible studies for this question.

1 finding from 1 review

Visual screening (oral visual inspection) by trained health workers vs No screening

Test performance (sensitivity and specificity) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…
1 finding from 1 review

Intervention not reported

Asthma symptoms measured using various techniques. · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

Quality of life Measured using various scales. · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

Exercise tolerance Measured using 6MWD · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

PEFR L/min · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

VEmax · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

VOmax · patients with asthma aged eight years or older
1 finding from 1 review

Intervention not reported

HRmax bpm · patients with asthma aged eight years or older
1 finding from 1 review

SiT for maintenance/relief vs higher‐dose ICS/LABA + SABA

Exacerbations requiring oral corticosteroids ‐ adults · Studies recruited adults and adolescents aged 12 and older with chronic asthma

SiT for maintenance/relief leads to lower patients with exacerbations requiring oral steroids compared with higher‐dose ICS/LABA + SABA (high certainty).

1 finding from 1 review

SiT for maintenance/relief vs higher‐dose ICS/LABA + SABA

Patients with serious adverse events · Studies recruited adults and adolescents aged 12 and older with chronic asthma

SiT for maintenance/relief showed no clear difference in patients with serious adverse events compared with higher‐dose ICS/LABA + SABA (moderate certainty).

1 finding from 1 review

SiT for maintenance/relief vs higher‐dose ICS/LABA + SABA

Patients with severe exacerbations (requiring hospitalisation or ER visit) · Studies recruited adults and adolescents aged 12 and older with chronic asthma

SiT for maintenance/relief leads to lower patients with severe exacerbations (requiring hospitalisation or ER… compared with higher‐dose ICS/LABA + SABA (high certainty).

1 finding from 1 review