Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Summary of findings: 1.25 mg/day plus rehabilitation vs placebo plus rehabilitation

Symptom free with activities of daily living (patient rated) ( · rotator cuff disease

Summary of findings: 1.25 mg/day plus rehabilitation showed no clear difference in symptom free with activities of daily living (patient rated) ( compared with placebo plus rehabilitation (low certainty).

1 finding from 1 review

Vitamin E (capsules 2000 IU/day in two divided doses) vs placebo

Number of participants experiencing any serious adverse events · people with Alzheimer's disease

Vitamin E (capsules 2000 IU/day in two divided doses) showed no clear difference in adverse events Number of participants reporting ≥ 1 serious adverse… compared with placebo (moderate certainty).

1 finding from 1 review

Vitamin E (capsules 2000 IU/day in two divided doses) vs placebo

Progression to Alzheimer's disease Number of people progressing to AD · MCI

Vitamin E (capsules 2000 IU/day in two divided doses) showed no clear difference in progression to Alzheimer's disease Number of people progressing to AD compared with placebo (moderate certainty).

1 finding from 1 review