Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

839 questions · 881 findings · 73 reviews

No studies found 246 · 27.9%GRADE not reported 156 · 17.7%Very low 219 · 24.9%Low 136 · 15.4%Moderate 90 · 10.2%High 34 · 3.9%

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Tooth loss · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review

Direct composite resin restoration vs Full-coverage metal-ceramic crown

Clinical failure (post dislodgement) · Participants with endodontically-treated permanent premolars restored with a carbon-fibre post (Category III)

Direct composite restoration (final restoration) showed no clear difference in clinical failure (post dislodgement) compared with full-coverage metal-ceramic crown; GRADE not reported.

1 finding from 1 review

Prebiotic vs placebo

Withdrawals due to adverse events · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)

It is very uncertain whether prebiotics changes withdrawals due to adverse events (14 days to 2 or 3 months) compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Failure to maintain clinical remission at end of study · Patients with quiescent ulcerative colitis

It is very uncertain whether antibiotics changes failure to maintain clinical remission at end of study compared with 5‐ASA (very low certainty).

1 finding from 1 review