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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,558 questions in 115 reviews · Vascular

current versions
No studies 346 · 22.2%Ungraded 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Direct thrombin inhibitors vs low molecular weight heparins
Major VTE events bilateral ascending venography1 · patients with prevention of venous thromboembolism following total hip or knee replacement
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of… (2010) · Cochrane
OR 0.91 [0.69, 1.19]11 studies · 17428 participantsLow
Direct thrombin inhibitors vs low molecular weight heparins
All‐cause Mortality events · patients with prevention of venous thromboembolism following total hip or knee replacement
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of… (2010) · Cochrane
OR 2.06 [1.1, 3.87]11 studies · 22065 participantsModerate
Direct thrombin inhibitors vs low molecular weight heparins
Total Bleeding events · patients with prevention of venous thromboembolism following total hip or knee replacement
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of… (2010) · Cochrane
OR 1.17 [0.98, 1.41]11 studies · 22109 participantsLow
Direct thrombin inhibitors vs low molecular weight heparins
ALT >3 times the upper normal limit · patients with prevention of venous thromboembolism following total hip or knee replacement
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of… (2010) · Cochrane
OR 0.41 [0.23, 0.72]7 studies · 12580 participantsLow
Direct thrombin inhibitors vs vitamin K antagonists
Major VTE events in TKR combined doses bilateral ascending venography · patients with prevention of venous thromboembolism following total hip or knee replacement
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of… (2010) · Cochrane
OR 0.85 [0.63, 1.15]3 studies · 4327 participantsLow
Direct thrombin inhibitors vs vitamin K antagonists
All‐cause Mortality events in TKR combined doses · patients with prevention of venous thromboembolism following total hip or knee replacement
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of… (2010) · Cochrane
OR 1.62 [0.57, 4.58]3 studies · 5243 participantsLow
Direct thrombin inhibitors vs vitamin K antagonists
Total Bleeding events in TKR combined doses · patients with prevention of venous thromboembolism following total hip or knee replacement
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of… (2010) · Cochrane
OR 1.26 [0.97, 1.62]3 studies · 5259 participantsLow
Direct thrombin inhibitors vs vitamin K antagonists
ALT >3 times the upper normal limit at the end of · patients with prevention of venous thromboembolism following total hip or knee replacement
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of… (2010) · Cochrane
OR 5.61 [1, 31.64]2 studies · 4267 participantsLow