Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Remote ischaemic preconditioning (RIPC) vs no RIPC

Limb loss (within 1 month after operation) · people undergoing elective major vascular surgery

Remote ischaemic preconditioning (RIPC) showed no clear difference in limb loss (within 1 month after operation) compared with no RIPC (low certainty).

1 finding from 1 review

Preconception lifestyle advice on weight vs usual care or attention control

Adverse events ‐ Gestational diabetes · women with infertility and obesity

It is very uncertain whether preconception lifestyle advice on weight changes adverse events ‐ Gestational diabetes compared with routine care or attention control (very low certainty).

1 finding from 1 review